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BestFIT Study

In this study, we are comparing five different fecal immunochemical tests (FITs) to determine how they compare with a doctor's findings during a routine colonoscopy. The FIT is a test that determines if there is hidden blood in the stool and is an alternative to colonoscopy for colorectal cancer screening when done annually.

Age & Gender

  • 50 years ~ 85 years
  • Male, Female


North Carolina (Statewide)

What will be asked of you

1. Sign an informed consent form. 2. Complete a health questionnaire. (will take ~10 minutes of your time) 3. Have one bowel movement and collect five different FITs prior to starting the prep for your colonoscopy. (will take ~15 minutes of your time) 4. Receive a $25 gift card for successful completion of the study steps.


$25 gift card

Total length of participation : up to 1 year

Looking for Healthy Volunteers

Requirements for healthy volunteers are different than for those with a specific condition. If you are interested in becoming a healthy volunteer for this study, use the below categories to determine if you are able to participate.

Able to participate:

  • You are having a screening or surveillance colonoscopy
  • You are 50-85 years of age

Not eligible if:

  • you have had rectal bleeding within the past two months.
  • you have been told by your doctor that you have an inflammatory bowel disease, such as ulcerative colitis or Crohn's disease.
  • you have a personal or family history of a hereditary polyposis syndrome.
  • you have previously had colon cancer or rectal cancer.
  • you have had a part or all of your colon removed for any reason

Contact the Team

Visit Location

100% Remote (online, phone, text)

Additional Study Information

Principal Investigator

Seth Crockett
Center for Gastrointestinal Biology and Disease

Study Type

Clinical or Medical

Study Topics

Cancer (Colorectal)
Stomach, Digestion and Gut Health
Healthy Volunteer or General Population
Women's Health
Men's Health

IRB Number




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