Systemic lupus erythematosus (SLE) is a severe, chronic autoimmune disorder that affects multiple organ systems and it is common for patients with SLE to also have other symptoms, including depression, chronic pain, and cognitive impairment (i.e., "brain fog"). Previous research shows that reducing these may lead to better quality of life for patients but current treatments for SLE are inadequate and the development of new therapies has been slow. Targeted stimulation modalities, such as non-invasive transcranial alternating current stimulation (tACS), have been shown to directly affect brain activity and improve depression, chronic pain, and cognitive impairment in patients that do not have SLE. The purpose of this clinical trial is to investigate the effects of tACS on patients diagnosed with SLE to see if they would also see a similar improvement in depression, chronic pain, and cognitive impairment.
1 screening visit and 1 MRI visit to verify eligibility, 5 consecutive days of stimulation, 1 2-week follow-up, 1 4-week follow up and 1 3-month online survey follow-up
$345 total by reloadable Visa gift card (10 installments)
Medicine-UNCP A Rheumatology
Clinical or Medical
Brain, Head, Nervous System
Mental and Emotional Health