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Pivotal study to assess the efficacy, safety and tolerability of dupilumab in patients with moderate-to- severe COPD with Type 2 inflammation (BOREAS)

The goal of this study is to evaluate an investigational medication and its effect on lung function and symptom control. Participants will either be given either the active medication or a placebo (inactive solution that does not contain medication) as an injection given every two weeks in clinic for one year.

Age & Gender

  • 40 years ~ 80 years
  • Male, Female

Location

North Carolina (Statewide)

Incentives

up to $2,260

In-person visits : 31
Total length of participation : 76 weeks

Looking for Specific Volunteers

Able to participate:

  • Have a diagnosis of COPD, emphysema, or chronic bronchitis
  • Currently on daily inhalers
  • History of two or more flares of COPD

Not eligible if:

  • Females who are currently pregnant or breastfeeding
  • Oxygen use for more than 12 hours a day
  • Evidence of Right Heart Failure

Contact the Team

Visit Location

100% Remote (online, phone, text)

Additional Study Information

Principal Investigator

Brad Drummond
Medicine-Pulmonary

Study Topics

Lungs and Breathing
Substance Use (tobacco, alcohol, opioids, etc)

IRB Number

19-0049

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