The purpose of this research study is to study immune responses against Neisseria gonorrhoeae in humans vaccinated with the US Food and Drug Administration (FDA)-approved outer membrane vesicle (OMV)-containing Neisseria meningitidis vaccine known as 4CMenB (trade name Bexsero™), which is given to provide protection from serious infections caused by a related bacteria. This study will test whether receiving this vaccine also leads to immune responses against N. gonorrhoeae. If there are immune responses to N. gonorrhoeae, it remains unknown whether those responses provide any protection from infection.
The first study visit will involve review of the informed consent, brief physical exam, and review of participant's medical history. At entry and week 5 participants will receive vaccination with the Meningitis B vaccine, Bexsero. These two visits, along with the final two follow-up visits will involve blood draws (4 in total), specimen collection, vital signs and a brief physical exam by a clinical research nurse.
up to $130 for completion of all study visits; plus parking vouchers during the study
Requirements for healthy volunteers are different than for those with a specific condition. If you are interested in becoming a healthy volunteer for this study, use the below categories to determine if you are able to participate.
Clinical or Medical
Child and Teen Health
Healthy Volunteer or General Population