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Non-invasive brain stimulation for Depression

In this study, we want to learn more about how non-invasive brain stimulation affects brain signals and the mood of people with depression. This technique is called transcranial alternating current stimulation (tACS).

Age & Gender

  • 18 years ~ 65 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)
  • Extended hours (M-F, early morning or evening)
  • Weekend hours, if needed


North Carolina (Statewide)

What will be asked of you

Study procedure 1. Screening: Screening session with questionnaires, which can be done remotely (2-3h) 2. Stimulation week: Five consecutive days with 40 min non-invasive brain stimulation, questionnaires, and brain signal recording (each day 2h). 3. Follow-up: Two weeks after last stimulation. Brain signal recording and questionnaires (90min).


Up to $255 Visa gift card, Parking passes available and limited transportation assistance available

In-person visits:
Phone or online visits:
Total length of participation:
3 weeks

Looking for Specific Volunteers

Able to participate:

  • Current Depression

Not eligible if:

  • Psychosis, Bipolar, OCD
  • PTSD or Eating disorder current or within last 6 months
  • Use of benzodiazepines or anti-epileptic drugs
  • You have a neurological disorder or traumatic brain injury
  • You are currently pregnant

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Visit Study Website

Primary Visit Location

Carolina Center for Neurostimulation
77 Vilcom Center Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

David Rubinow

Study Type

Clinical or Medical

Study Topics

Brain, Head, Nervous System
Mental and Emotional Health

IRB Number




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