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SALTY - Asthma Study

Mucus plugging is one of the causes of an asthma exacerbation, or "attack". In this study, we are looking for people who have asthma that requires daily medication to keep under control. We would ask you to inhale a strong saltwater solution to see how your lungs clear the mucus.

Age & Gender

  • 18 years ~ 60 years
  • Male, Female

Visit Availability

  • Standard business hours (M-F, 8-5)


North Carolina (Statewide)

What will be asked of you

We will check your lung function at each visit. You will inhale a salt water mist at 2 different concentrations, and then you will undergo a scan to see how the mucus clears from your lungs. You will need to come back the next day for a short follow up visit. We will ask you to use albuterol at each visit as well.


If you complete participation you will earn $875

In-person visits:
Total length of participation:
3 1/2 months

Looking for Specific Volunteers

Able to participate:

  • You have asthma that is well-controlled using a combination inhaler (bronchodilator and inhaled steroids)
  • You are otherwise healthy
  • Proof of COVID-19 vaccination

Not eligible if:

  • Pregnant or nursing a baby
  • No cold or flu symptoms
  • No other major, uncontrolled medical problems.

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Center for Environmenal Medicine, Asthma and Lung Biology (CEMALB)
U.S. EPA Human Studies Facility (UNC-Chapel Hill)
104 Mason Farm Rd, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

David Peden
Center for Environmental Medicine Asthma and Lung Biology (CEMALB)

Study Type

Clinical or Medical

Study Topics

Lungs and Breathing

IRB Number




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