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Ravulizumab/placebo for Lupus Nephritis or IgA Nephropathy

Evaluate the Efficacy and Safety of Ravulizumab in Adult Participants With Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN)

Age & Gender

  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

The study will have blood pressure measurements, physical exams, blood draws, urine collection including 24 hour urine collection, quality of life surveys and study drug/placebo intravenous infusion. You will also need to be vaccinated against some specific diseases.

Incentives

information provided upon request, mileage reimbursement

In-person visits:
18
Phone or online visits:
2
Total length of participation:
1 year and 8 months

Looking for Specific Volunteers

Able to participate:

  • Lupus nephritis or IgA Nephropathy
  • protein present in the urine
  • not transplanted or planning to be transplanted
  • not on dialysis or soon to start dialysis

Not eligible if:

  • you are pregnant or breastfeeding or planning to be pregnant

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Amy Mottl
Medicine-Nephrology

Study Type

Clinical or Medical
Interventional

Study Topics

Kidneys and Liver

IRB Number

20-3399

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