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Belimumab and Rituximab Compared to Rituximab Alone for the Treatment of Primary Membranous Nephropathy

This is a three-year research study for people with primary membranous nephropathy (primary MN). The study will test if combining belimumab and rituximab is effective in treating Primary MN.

Age & Gender

  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Extended hours (M-F, early morning or evening)


North Carolina (Statewide)

What will be asked of you

At each visit, you will meet with a member of the study team and answer questions about your health and your medications. We will take your vitals. Some visits will include the rituximab infusion, the belimumab or placebo being injected under your skin, a 24 hour urine collection, some questionnaires..


$50 per visit

In-person visits:
Total length of participation:
3 years

Looking for Specific Volunteers

Able to participate:

  • you are not on dialysis and your doctor has not mentioned you will soon need to start dialysis.
  • you have not had a kidney transplant
  • you still have protein spilling in your urine
  • if you know your kidney function level numbers: your eGFR must be >30

Not eligible if:

  • you have been treated with Rituximab in the last 12 months
  • you have been treated with a medication decreasing your immune system in the last 30 days

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Burnett-Womack Building, 160 Dental Cir, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Vimal Derebail

Study Type

Clinical or Medical

Study Topics

Kidneys and Liver

IRB Number




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