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Non-invasive Brain Stimulation for Depression Study

We are investigating how the brain works when thinking about rewards and losses. We are delivering low-current electrical stimulation to better understand brain activity involved in decision-making.

Age & Gender

  • 18 years ~ 65 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)
  • Extended hours (M-F, early morning or evening)
  • Weekend hours, if needed


North Carolina (Statewide)

What will be asked of you

At the first study visit, you will meet with a member of the study team and conduct interviews to understand your experience with depression. Then, we will record electrical brain activity and deliver electrical brain stimulation during some decision-making tasks. In the second session, you will undergo an MRI scan. Finally, an at-home saliva sample kit is provided to understand how hormones influence brain activity.


Up to $130

In-person visits:
Total length of participation:
1 week

Looking for Specific Volunteers

Able to participate:

  • Major depressive disorder
  • Low suicide risk

Not eligible if:

  • Substance use disorder
  • Symptoms of psychosis
  • Personal or family history of epilepsy
  • Attention deficit disorder
  • Neurological disorders

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Dawson Hall Building (Vilcom Center)
77 Vilcom Center Dr, Chapel Hill, NC 27514, USA

Secondary Visit Location

Biomedical Research Imaging Center
Marsico Hall (UNC-Chapel Hill)
125 Mason Farm Rd, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Flavio Frohlich
Psychiatry - Research

Study Type

Clinical or Medical

Study Topics

Mental and Emotional Health

IRB Number


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