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EoE Tooth Fairy Study: Environmental Risk Factors for Eosinophilic Esophagitis (EoE)

This is a study to find out how early life experiences and exposures can affect a child's likelihood to develop Eosinophilic Esophagitis (EoE) . EoE is a disease that causes abdominal pain, vomiting, heartburn, failure to thrive, and esophageal inflammation in children. We want to learn if exposure to antibiotics, breastfeeding, exposure to pets, smoke, etc. have any relation to EoE.

Age & Gender

  • 0 years ~ 17 years
  • Male, Female, Gender Inclusive

Location

New York, North Carolina (Statewide), Pennsylvania, South Carolina

What will be asked of you

You will be asked to provide some information about your child and their medical history. We will also ask for permission for your child to submit a sample of saliva for a DNA test and a lost baby tooth. A member of the study team will call you to discuss your child's medical history, and you will be provided with a link to online questionnaires.

Incentives

Up to $50, details provided upon request

Total length of participation:
One time survey and sample collection

Looking for Specific Volunteers

Able to participate:

  • Your child is under 18 years old
  • Your child has lost at least 1 baby tooth
  • You currently live with your child
  • Your child has been diagnosed with EoE at a UNC Hospitals Clinic

Not eligible if:

  • You are unable to read or understand English
  • You are unable to provide at least one of your child's baby teeth
  • Your child has been diagnosed with non-esophageal eosinophilic gastrointestinal diseases (EGIDs), cancer, or other serious chronic illness

Looking for Healthy Volunteers

Requirements for healthy volunteers are different than for those with a specific condition. If you are interested in becoming a healthy volunteer for this study, use the below categories to determine if you are able to participate.

Able to participate:

  • Your child is under 18 years old
  • Your child has lost at least 1 baby tooth
  • You currently live with your child
  • Your child has received care at a UNC Hospitals specialty clinic

Not eligible if:

  • You are unable to read or understand English
  • You are unable to provide at least one of your child's deciduous (baby) tooth
  • Your child has been diagnosed with non-esophageal eosinophilic gastrointestinal diseases (EGIDs), cancer, or other serious chronic illness

Contact the Team

Visit Location

100% Remote (online, phone, text)

Additional Study Information

Principal Investigator

Evan Dellon
Medicine-Gastroenterology

Study Type

Clinical or Medical
Registry

Study Topics

Child and Teen Health
Stomach, Digestion and Gut Health
Environment
Genetics and Genetic Disorders
Healthy Volunteer or General Population
Mouth and Teeth
Parents of Children
Rare Diseases

IRB Number

21-0100

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