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ProNET: Psychosis Risk Outcomes Network

The purpose of this research study is to better understand the cause and course of clinical high-risk symptoms and to monitor participants for the possible development of mental illnesses such as psychosis. Clinical high-risk symptoms can include feeling low in mood, feeling like something odd is going on, feeling suspicious, or seeing or hearing things that the person knows aren't there. Some people might worry that their thoughts are being heard or might be having more difficulty than usual coping with work, school, or relationships. For some, these early symptoms may become more severe over time. For others, the symptoms may stay the same, decrease, or go away entirely. Improving our knowledge about these symptoms and risk factors and the way that they change over time may help researchers and clinicians predict possible outcomes for individual patients and develop treatment plans that are best suited to individual patients.

Age & Gender

  • 12 years ~ 30 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)


North Carolina (Statewide)

What will be asked of you

At each visit, you will meet with a member of the study team and complete clinical assessments related to your recent experiences. The study also involves neurocognitive assessments, 2 blood draws, 2 MRIs, and 2 EEGs, among other assessments.


$30 per hour

In-person visits:
Phone or online visits:
Total length of participation:
2 years

Looking for Specific Volunteers

Able to participate:

  • You are experiencing changes in your thinking or perception

Not eligible if:

  • You have been diagnosed with psychosis or a psychotic disorder

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Visit Study Website

Primary Visit Location

Medical School Wing D (UNC-Chapel Hill)
336 Emergency Room Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Diana Perkins
Psychiatry - Center of Excellence - Outreach and Support Intervention Services (OASIS)

Study Type

Clinical or Medical

Study Topics

Healthy Volunteer or General Population
Mental and Emotional Health

IRB Number


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