Individuals with a history of anterior cruciate ligament (ACL) injury and have had an ACL reconstruction (ACLR) are at a greater risk for developing osteoarthritis. The greater risk for developing osteoarthritis is likely caused by too little force or physical activity applied to the knee during weightbearing tasks such as walking. To reduce this decrease in forces during walking following an ACLR, we must first develop effective treatments that can train a person to walk in a way that reduces their risk of developing osteoarthritis. The purpose of this research study is to determine the feasibility and the initial effects of a 6-week training program designed to improve walking mechanics by targeting risk factors related to osteoarthritis development. *This study is a collaboration with the UNC Sports Medicine Institute*
You are being asked to be in the study because you are between the ages of 16-35 and it has been 6 to 60 months since your anterior cruciate ligament reconstruction (ACLR). You would attend 18 sessions of training over a 6-week period and will have 3 follow-up assessments at 6, 8 weeks and 6 months. If you screen into the study there would be a series of tests related to your walking biomechanics, biomarkers from a blood draw and an MRI assessment to assess your knee cartilage. MRIs will only be conducted in adult participants (ages 18 and older). Each of the training sessions would involve you walking on an instrumented treadmill while your biomechanics are assessed. The follow-up assessments would involve a series of tests related to your walking biomechanics, biomarkers from a blood draw and urine and an MRI assessment.
$310 for Completing all Sessions
MOTION Science Institute
Fetzer Hall (UNC-Chapel Hill)
210 South Rd, Chapel Hill, NC 27514, USA
Brian Pietrosimone
Exercise and Sport Science
Clinical or Medical
Interventional
Bones, Joints, Muscles
Minority Health
Pain
Parents of Children
Wellness and Lifestyle
Women's Health
Men's Health
Movement
UNC or UNC Health employees
UNC Students (undergrad, grad, professional)
21-1489
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