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CHronic nonbacterial Osteomyelitis International Registry (CHOIR)

The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease and the responses of patients to different clinical managements over 5 years.

Age & Gender

  • 0 years ~ 21 years
  • Male, Female, Gender Inclusive


North Carolina (Statewide)

What will be asked of you

At each of your regularly scheduled clinic visit, the rheumatologist or study coordinator will ask you to complete questionnaires regarding your disease and how it effects you.

In-person visits:
Total length of participation:
5 years

Looking for Specific Volunteers

Able to participate:

  • chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO)

Not eligible if:

  • Above the age of 21

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

NC Memorial Hospital
UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Eveline Wu
Pediatrics - Children's Research Institute

Study Type

Behavioral or Social

Study Topics

Bones, Joints, Muscles
Chronic Conditions
Immune System/Infections
Rare Diseases

IRB Number


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