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Bacterial Disease Vaccine Development Research Study

We are studying whether the FDA approved vaccine, BexseroTM, which is already proven to provide protection against Meningitis B, will also provide protection against the bacteria that causes gonorrhea. Researchers at UNC-Chapel Hill have been working for over two decades to develop preventative measures for a common STD, Gonorrhea. Currently, antibiotics are available that are highly effective for curing Gonorrhea, but antibiotic resistance in the bacteria that causes Gonorrhea is on the rise and no vaccine has been proven in a clinical trial to protect individuals from Gonorrhea.

Age & Gender

  • 18 years ~ 35 years
  • Male

Visit Availability

  • Standard business hours (M-F, 8-5)
  • Weekend hours, if needed


North Carolina (Alamance, Chatham, Durham, Orange, Wake)

What will be asked of you

You will be asked to receive 3 FDA-approved vaccinations and a controlled challenge with bacteria to test protection. At most visits you will be asked to provide a urine sample. In addition, a few of the visits will require a blood draw.


up to $1100 , Monetary reimbursement for extensive travel to research site (based on mileage) and receipt of 3 FDA-approved vaccines free of charge

In-person visits:
up to 18 visits done in-person
Phone or online visits:
3 visits done by phone
Total length of participation:
up to 7 months

Looking for Healthy Volunteers

Requirements for healthy volunteers are different than for those with a specific condition. If you are interested in becoming a healthy volunteer for this study, use the below categories to determine if you are able to participate.

Able to participate:

  • male-bodied
  • between the ages of 18-35 years
  • are able to return to the research site daily for up to 10 days in a row
  • reside in the Chapel Hill area
  • generally healthy

Not eligible if:

  • female-bodied
  • any known autoimmune disorder or immunodeficiency
  • allergy to penicillin, cephalosporins, ciprofloxacin, or lidocaine
  • donated blood or other blood products in the past month

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Secondary Visit Location

UNC Global Clinical Research North (GCRN)
1828 MLK Jr Blvd, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Alex Duncan
Institute for Global Health and Infectious Diseases

Study Type

Clinical or Medical

Study Topics

Healthy Volunteer or General Population
Sexual and/or Reproductive Health
Wellness and Lifestyle
Men's Health

IRB Number




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