NERD is a disease that causes occasional heartburn (called "episodic heartburn"). This is often described as a burning sensation in your chest or throat (behind your breast bone). The purpose of this study is to learn if an experimental drug (vonoprazan) can be a potential treatment for NERD.
You will be asked to answer questions about your heartburn during the study. Most in-person visits will take approximately 1 hour. At one visit, you will undergo an upper endoscopy (a test that shows your doctor the inside of your throat and stomach). You will also receive the study drug (vonoprazan or placebo) for 4 weeks. After this, you will receive the study drug for up to an additional 20 weeks. After this, you will be asked to come into the clinic for one last visit.
Information provided upon request
Clinical or Medical
Stomach, Digestion and Gut Health
Eating, Nutrition, and Metabolism
Healthy Volunteer or General Population