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Individualized Diet Elimintation for Treatment of Eosinophilic Esophagitis (EoE)

To see if a new method for identifying food allergies works in determining what foods trigger an allergic condition of the esophagus (eosinophilic esophagitis EoE) and therefore can help treat EoE if they are removed from your diet.

Age & Gender

  • 16 years ~ 80 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)
  • Extended hours (M-F, early morning or evening)
  • Visits can be combined with regular clinical appointments


North Carolina (Statewide)

What will be asked of you

You will complete questionnaires and provide a blood and tissue sample prior to your clinically scheduled upper endoscopy procedure. You will be randomized to an individualized diet elimination therapy or a sham(pretend) diet elimination therapy. You will meet with a study dietician to review your assigned diet and then follow the diet elimination therapy for 8 weeks. You will complete weekly questionnaires and check-in with the study team virtually. You will have a visit with the dietician at 4 weeks and 8 weeks (can also be virtual) and return for an end of study upper endoscopy as part of your clinical care at 8 weeks at which time additional questionnaires, blood, and biopsies will be completed for the study.


Up to $100

In-person visits:
Phone or online visits:
up to 6
Total length of participation:
2-4 months

Looking for Specific Volunteers

Able to participate:

  • You have been diagnosed with eosinophilic esophagitis (EoE)
  • You are interested in receiving diet elimination therapy for your EoE
  • You are between 16 and 80 years old

Not eligible if:

  • You are older than 80 years old
  • You have previously tried diet elimination therapy for treatment of your EoE
  • You have a bleeding disorder
  • Are unable to read or understand English
  • Are pregnant or breastfeeding

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Secondary Visit Location

Endoscopy Center
UNC Meadowmont
300 Meadowmont Village Cir, Chapel Hill, NC 27517, USA

Additional Study Information

Principal Investigator

Evan Dellon

Study Type

Clinical or Medical

Study Topics

Stomach, Digestion and Gut Health
Ear, Nose, and Throat

IRB Number




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