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This research study is a way to find out if the Study Drug, VX-147 is safe and if it works to help people with APOL-1 mediated Chronic Kidney Disease.

Age & Gender

  • 18 years ~ 60 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)
  • In-home visits available
  • Visits can be combined with regular clinical appointments


North Carolina (Statewide)

What will be asked of you

Study visits will be like regular doctor appointments. At these visits, we will measure your vital signs (blood pressure, weight, height), conduct an ECG (test to measure heart function), the study doctor will complete a brief physical exam, and we will collect blood and urine samples.


Study payments will be distributed using a reloadable debit card

In-person visits:
Phone or online visits:
Total length of participation:
4 years

Looking for Specific Volunteers

Able to participate:

  • Between the ages of 18 and 60
  • Have APOL1-mediated Chronic Kidney Disease

Not eligible if:

  • Had a transplant
  • Have cancer
  • Had a stroke or heart attack within the past 6 months

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Visit Study Website

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Secondary Visit Location

Nephrology Outpatient Center
UNC Eastowne Medical Office Building
100 Eastowne Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Vimal Derebail

Study Type

Clinical or Medical

Study Topics

Kidneys and Liver
Rare Diseases

IRB Number




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