Did you know that over 250 million persons are affected by Osteoarthritis? It is the leading cause of disability among adults and has no cure. Prevention of OA is preferable to treatment and females are affected at nearly twice the rate as males. If you are a female, at least 50 years of age, overweight, with no or occasional knee pain, you may be able to participate in a research study to find out if a diet and exercise program or a health education program prevent knee OA.

If you are healthy and between the ages of 18-55 years, you may be eligible to participate in a research study to find out how sugar affects the brain of individuals who carry certain genetic variants.

Are you scheduled for weight loss surgery within the next 12 months? You may be able to take part in a research study to help us learn more about your metabolic hormones, eating behaviors, stress, and weight loss before and after your surgery.

In this study, we want to learn more about two strategies that interrupt sitting: walking and seated pedaling. Sitting, or sedentary behavior, is a public health crisis that increases all causes of mortality and doubles the risk of cardiovascular disease. Interrupting sitting may help reduce the cardiovascular disease risk associated with uninterrupted bouts of sitting.

Nutrition is not one-size-fits-all. Nutrition, or the foods we eat, can help prevent and fight conditions such as high blood pressure, diabetes, stroke, and more. However, we all live in different environments, we come from different cultures, and each of us is starting from a different place with our health. Additionally, everyone breaks down food differently. Join the Nutrition for Precision Health research study to help researchers learn how our genes, cultural backgrounds, and environments affect our bodies' responses to food. Compensation provided.

During puberty, adolescents grow and change a lot which may make life seem more stressful and emotional. Male and female adolescents experience the changes associated with puberty differently, possibly because of different responses to changes in hormones, including testosterone and estrogen. We are interested in learning more about the role of these hormones in regulating emotional processing and mood symptoms, and whether a mobile training program can help improve mood during the pubertal transition. Participation is 8 weeks with two monthly follow-up surveys. Compensation provided.

We want to learn how people's brains adapt when responding to various food stimuli and decision-making processes. We also want to learn about brain responses to food and beverage consumption. To do this, we will use taste tests, surveys, behavioral tasks, and neuroimaging (fMRI scan).

Leveraging our decades of experience studying the acute and chronic effects of traumatic brain injury (TBI) and concussion, our investigative team propose an innovative, translational approach that bridges both preclinical and clinical studies. We propose testing multiple potential preventative and therapeutic strategies in the preclinical setting, while simultaneously conducting a prospective, longitudinal study of neurologic health outcomes associated with concussion and sub-concussive exposure in former NFL players. Our prior studies of former NFL players over the past 15 years provide us with a unique opportunity to conduct a truly prospective, longitudinal study of long-term neurologic health outcomes and determine any possible association with concussion and repetitive sub-concussive exposure. In parallel, we have developed animal models of repeated concussions (repetitive mild TBI [rmTBI]) and chronic traumatic encephalopathy (CTE). We have studied the effects of readily translatable preventative and therapeutic strategies, including the N-methyl-D-aspartate (NMDA) receptor antagonist memantine, low dose carbon monoxide

In this study, we want to learn more about the experiences and activities of high school-aged youth after a neurological event. This study will also help us to understand the perspectives of youth and a parent/caregiver through photos and stories.

We want to learn more about how executive functioning differs between children with ADHD, ASD, or neither. We have finished recruiting for our ADHD and typically developing groups but are still recruiting autistic children to be a part of our study. Children will complete an iPad-based measure of executive functioning and complete various tasks while their brain activity is being monitored using EEG. We will also complete a short eye-tracking task. Parents will fill out different forms to get an understanding of each child's developmental history and current behaviors.