To test the safety of the trial drug, MK-8527 compared to emtricitabine/tenofovir (FTC/TDF) and to see how well MK-8527 works to reduce the chance of getting HIV-1 infection compared to FTC/TDF.

The purpose of this study is to understand academic buoyancy in undergraduates at a rigorous university. College students face academic stress, burnout, depressive symptoms, and feelings of inadequacy. Findings will improve understanding of how students respond to academic stress and perceived inadequacy, and what they need to become academically buoyant.

The purpose of this study is to understand social perception.

The study is designed to investigate how people find and learn information using digital search systems. With the World Wide Web and other digital tools, tons of information is placed at the tips of our fingers. For many years, search engines were the predominant tool for information retrieval on the web. However, recent developments in artificial intelligence (AI) have resulted in increasing use of AI chatbots to find and learn information. This study compares how users interact with search engines and chatbots to find and learn information to better understand the cognitive processes involved in digital search and how these systems support learning.

The purpose of this research study is to investigate the relationship between sleep brain wave patterns and peripheral glucose (sugar) levels in individuals with and without type 2 diabetes mellitus (T2DM). Participants will undergo continuous glucose monitoring (CGM) using a CGM device for up to two weeks before an in-laboratory sleep study which is part of routine medical care at UNC to examine how sugar levels fluctuate during sleep and how these fluctuations relate to brain wave activity

In this project we are interested in how reputations affect international cooperation. In particular, we are interested in studying how the cost of cooperation changes for countries who fail to uphold their international commitments. We anticipate that this happens via two mechanisms. The first is direct: a change in beliefs about the state's reliability in the eyes of other countries. The second is indirect: a concern that failing to punish a state for non-cooperative behavior will invite more non-cooperative behavior in the future. States, we suspect, are thus concerned with developing a reputation for tolerating non-cooperative behavior. We use survey experiments on the US public and elites to study these questions.

The purpose of this research study is to assess the impact of student interns on the implementation of new services at independent community pharmacies. Identifying what type of support pharmacies need to integrate programs into workflow and successfully engage in the program will allow future programs to follow a similar framework.

We are interested in studying how people behave at work. This study consists of one online survey where you will be asked to read one news article and answer brief questions about workplace behaviors.

We investigate how reports from election observation missions (EOMs) shape perceptions of election integrity. We also investigate the effect of government criticism of EOMs.

The purpose of this study is to determine if performing a paracervical block, or placing local anesthetic around the cervix, at the time of vaginal hysterectomy and prolapse repair reduces the amount of opioid medications that patients need and pain that patients feel after surgery. Even short term use of opioid medications can be associated with side effects such as constipation, nausea, somnolence, or dependence.