To test the safety of the trial drug, MK-8527 compared to emtricitabine/tenofovir (FTC/TDF) and to see how well MK-8527 works to reduce the chance of getting HIV-1 infection compared to FTC/TDF.

The United States is facing a worsening physician shortage that particularly affects people living in rural or underserved communities. One strategy used to address this problem is clinical exposure programs for students in high school, college, and/or medical school. Research currently suggests that these programs could influence participants' interest in medicine, specialty choice, and practice location preferences. Mentoring in Medicine is a summer clinical exposure program that targets college students in the Johnstown area of Pennsylvania. This region of the state is socioeconomically disadvantaged and medically underserved. No formal follow-up has been conducted on the participants since the program began in 2004. We plan on surveying these past participants to examine their academic and career interests and outcomes. We will also use physician databases to determine career outcomes. This data will help contribute to the body of evidence regarding educational interventions to improve medical shortages in the United States.

The purpose of this research study is to collect data about attitudes towards social topics in the news.

To collect and store specimens from people who have been exposed to a natural or manmade disaster.

The main objective of this study is to develop methods for forecasting passenger waiting times in TSA lines at RDU airport.

The purpose of this study is to characterize the natural history of DRPLA patients using a variety of clinical and biomarker modalities and to identify genetic factors, biomarkers, and clinical measures that could predict disease progression.

Cities are hot during daytime in summer time - much hotter than their surrounding vegetated, often forested rural areas. This effect, the Urban Heat Island Effect, is determined by building materials, human activity, and urban vegetation. But how does it affect individual thermal comfort? We are interested in understanding relationships between temperature and thermal comfort in urban areas.

Participants in this study are asked to read a list of words, then sort the words into categories based on their vowel sounds (ignoring letters). We are trying to find out how different two sounds have to be acoustically before speakers consider them to be linguistically different.

This project studies how our ability to hear with two ears changes as we age or develop hearing loss.

The purpose of this study is to assess the extent to which engaging teachers in iterative design processes with scientists increases their content knowledge of and self-efficacy for incorporating current biomedical science into their teaching. This study includes a professional development program with a teacher-driven curriculum development component.