• Home
  • Search Results

Research Studies

UNC-Chapel Hill Division of Pulmonary Diseases and Critical Care Medicine

47 studies match your search
By physician referral or invitation only

A Phase I, Randomized, Standard-Care-Controlled Study of the Safety and Efficacy of Intravenous Delivery of Lung Spheroid Cells in Patients with Idiopathic Pulmonary Fibrosis

Primary: To demonstrate the safety of autologous LSCs administered by intravenous infusion in patients with idiopathic pulmonary fibrosis. Secondary: To demonstrate the efficacy of autologous LSCs administered by intravenous infusion in patients with idiopathic pulmonary fibrosis.

Age & Gender
  • 50 years ~ 80 years
  • Male, Female, Gender Inclusive
Study Interest
  • Lungs and Breathing
  • Rare Diseases
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

PAH inhaled therapy Study

This study is testing a new medication for patients who have group 1 PAH.

Age & Gender
  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Lungs and Breathing
  • Rare Diseases
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Idiopathic Pulmonary Fibrosis (IPF) and Chronic Fibrosing Interstitial Lung Disease with Progressive Phenotype (ILD) Registry

This registry will collect data on the strategies used to achieve a diagnosis of Idiopathic Pulmonary Fibrosis (IPF) and Chronic Fibrosing Interstitial Lung Disease with Progressive Phenotype (ILD) and the treatment and management efforts applied throughout study follow-up, clinical outcome events and patient reported outcome data. Blood samples will be collected periodically throughout the study for use in future research efforts. For participants with non-IPF, chronic fibrosing ILD with progressive phenotype, HRCT images will be collected throughout the study for use in future research efforts.

Age & Gender
  • 40 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Lungs and Breathing
  • Rare Diseases
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

GEMINI-NSCLC: TEMPUS NSCLC SURVEILLANCE STUDY

The purpose of this study is to evaluate a new test being developed by Tempus for patients with Non-Small Cell Lung Cancer (NSCLC). The goal of this new test is to predict the likelihood of a patient's cancer coming back after treatment, and to further explore changes in patient's tumors throughout treatment to see how they respond.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lung)
  • Lungs and Breathing
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

TEMPUS Small Cell Lung Cancer OBSERVATIONAL STUDY (Sculptor)

This is an exploratory study in cancer biomarker research, hoping to identify cell-signaling using DNA, in patients with SCLC.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lung)
  • Lungs and Breathing
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Lung Imaging Study for Cystic Fibrosis

This study will test how effectively changes in lung structure and function can be detected with a new inhaled gas combined with a MRI.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Lungs and Breathing
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

COVID Immunology Study

The virus that causes COVID-19 disease infects many people, but only some get sick. We want to understand how COVID affects the immune system and what makes severe COVID infections different from other diseases that cause hospitalization and breathing problems. We collect samples of blood, sputum, urine, and stool from patients in the hospital to learn how COVID affects cells and molecules of the immune system.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Immune System/Infections
  • Lungs and Breathing
  • Microbiome
  • COVID-19
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

PATIENCE - NTM Study

The primary objective of PATIENCE is to develop a standardized approach to the treatment of NTM in CF patients with a diagnosis of NTM disease. The secondary objectives are to: - Evaluate the feasibility and tolerability of a standardized treatment protocol for NTM disease - Evaluate effectiveness of a standardized NTM disease treatment protocol to serve as baseline/reference estimates of endpoints in clinical care and future therapeutic trials - Support biomarker development for markers of NTM treatment response through banking of clinical specimens and NTM isolates linked with outcomes data - Characterize clinical features of patients achieving treatment success compared to those unresponsive to treatment

Age & Gender
  • 6 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Genetics and Genetic Disorders
  • Lungs and Breathing
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Nasal Swab to Evaluate Lung Cancer Risk

The DNA that we can test from a nasal swab, can help us determine a patient's lung cancer risk. For patients with new lung nodules found on CT scans, we are offering this nasal swab test and collecting data on how physicians use test results to help assess risk and determine treatment strategies.

Age & Gender
  • 29 years ~ 85 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lung)
  • Lungs and Breathing
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Delirium Tele-medicine Validation Study

We don't know whether discharging patients with active delirium (aka confusion) home is appropriate. Returning patients to their home may lead to improvement and quicker delirium resolution. Alternately, it may be harmful as delirious patients may not be able to appropriately care for themselves in the home environment or follow discharge instructions. Consequently, they may get sicker, requiring hospital readmission or worse. Currently, there is no good way to assess delirium in the home setting. This greatly limits the ability to monitor and study this vulnerable population. The ability to perform in-home delirium assessments will prove invaluable to researchers investigating the a-propriateness of discharging actively delirious patients' home versus keeping them in the hospital until resolution of their delirium. Further, it will provide a method for clinicians to perform quick, remote delirium assessments of their patients.

Age & Gender
  • 65 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Behavior
Visit Location
100% Remote (online, phone, text)
Research for Me logo

Copyright © 2013-2022 The NC TraCS Institute, the integrated home of the NIH Clinical and Translational Science Awards (CTSA) Program at UNC-CH.  This website is made possible by CTSA Grant UL1TR002489 and the National Center for Advancing Translational Sciences.

Questions?

  • This email address is being protected from spambots. You need JavaScript enabled to view it.
logo for the North Carolina Translational and Clinical Sciences Institute
logo for UNC Health
logo for UNC School of Medicine
logo for UNC Research