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UNC-Chapel Hill Department of Radiation Oncology

14 studies match your search
Not currently enrolling

PSMA-PET/MRI Low and Intermediate-Risk Target Volume Pilot Study

This is a pilot trial testing the safety and feasibility of using PSMA-PET and mpMRI to optimize radiotherapy targets for patients with low-risk or intermediate-risk prostate cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male
Study Interest
  • Cancer (Prostate)

Biomarker for cervical cancer screening study

To determine if plasma circulating HPV DNA (cHPVDNA) has potential as a non-invasive biomarker for identification and treatment monitoring of cervical intraepithelial neoplasia grades 2-3 by characterizing correlation between plasma cHPVDNA levels and cervical intraepithelial neoplasia grade prior to intervention and after excision.

Age & Gender
  • 18 years ~ 99 years
  • Female
Study Interest
  • Cancer (Cervical)
  • Immune System/Infections
  • Sexual and/or Reproductive Health
  • Women's Health
Not currently enrolling

Pancreatic Cancer with Electron intraoperative Radiation therapy

We want to research how well Intraoperative Radiation therapy during surgery works in treating pancreatic cancer after 3-6 months of chemotherapy and external radiation therapy. This multi-center, phase II study will enroll patients with either borderline-resectable or locally advanced unresectable pancreatic cancer who have already received chemotherapy and radiation therapy. Patients will be stratified for analysis based on the extent of their disease at initial diagnosis. All patients will receive the same protocol-specified intervention of electron beam intraoperative radiation therapy (IORT). IORT will be administered as determined to be best practice by the study doctor. IORT will be administered in 1 day.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Pancreatic)
Open

Prospective Investigation of Biomarkers in HPV+ Oropharyngeal Squamous Cell Carcinoma

Have you been diagnosed with oropharyngeal (tonsil or tongue base) cancer. If so, you may be able to take part in a research study testing markers to determine who may be appropriate for less aggressive therapy and markers to determine if recurrent tumors can be detected earlier.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Head and Neck)
Visit Location
100% Remote (online, phone, text)
Coming Soon

Testing whether blood and urine can be used to detect ctHPVDNA in women with known history of cervical cancer

To see whether a blood and urine test can be used to detect circulating tumor HPV DNA in women with cervical cancer. The hope is to be able to use this test in the future to help find cervical cancer earlier and detect any new cancer in people previously treatment for it.

Age & Gender
  • 18 years ~ 99 years
  • Female, Focus on recruitment of transgender men
Study Interest
  • Cancer (Cervical)
  • Women's Health
Visit Location
100% Remote (online, phone, text)

A Prospective Comparative Study of Outcomes with Proton and Photon Radiation in Prostate Cancer

Two types of radiation treatment are routinely used for prostate cancer: photon (X-ray )therapy and proton therapy. The purpose of this study is to directly compare the two therapies to determine which one has better disease control and fewer patient-reported and physician-reported side effects.

Age & Gender
  • 18 years ~ 99 years
  • Male
Study Interest
  • Cancer (Prostate)
  • Men's Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Identifying Workplace Stressors at UNC that Lead to Burnout

Burnout within the health care setting is a known problem. The COVID-19 pandemic has lead to dramatic changes in the health care workplace and may lead to worsening burnout. This study aims to identify the most worrisome workplace stressors at UNC across departments so that changes can be made to address burnout.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Opinions and Perceptions
  • Social or Workplace Dynamics
  • COVID-19
  • and 2 more
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Feasibility of Electronic Questionnaires for Patients With Gynecologic Cancer

The goal of this study is to see if it is feasible to use electronic questionnaires to measure patient related outcomes before, during, and after radiation for gynecologic cancer in a high-volume radiation oncology clinic.

Age & Gender
  • 18 years ~ 99 years
  • Female
Study Interest
  • Cancer (Cervical, Other Cancers, Uterine (endometrial))
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Observational Study of GammaTile Therapy

This is a non-interventional, observational study to collect data on survival, quality of life, and other follow-up information on patients who receive GammaTile therapy.

Age & Gender
  • 0 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Cancer (Brain and Other Nervous System)
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Assessing usability of electronic workplace violence reporting tool and associated cognitive workload

The purpose of this study is to evaluate the usability of current SAFE Employee incident report and inform the design of an enhanced version of the report.

Age & Gender
  • 20 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • UNC or UNC Health employees
Visit Location
100% Remote (online, phone, text)
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