This is a pilot trial testing the safety and feasibility of using PSMA-PET and mpMRI to optimize radiotherapy targets for patients with low-risk or intermediate-risk prostate cancer.

To determine if plasma circulating HPV DNA (cHPVDNA) has potential as a non-invasive biomarker for identification and treatment monitoring of cervical intraepithelial neoplasia grades 2-3 by characterizing correlation between plasma cHPVDNA levels and cervical intraepithelial neoplasia grade prior to intervention and after excision.

We want to research how well Intraoperative Radiation therapy during surgery works in treating pancreatic cancer after 3-6 months of chemotherapy and external radiation therapy. This multi-center, phase II study will enroll patients with either borderline-resectable or locally advanced unresectable pancreatic cancer who have already received chemotherapy and radiation therapy. Patients will be stratified for analysis based on the extent of their disease at initial diagnosis. All patients will receive the same protocol-specified intervention of electron beam intraoperative radiation therapy (IORT). IORT will be administered as determined to be best practice by the study doctor. IORT will be administered in 1 day.

Have you been diagnosed with oropharyngeal (tonsil or tongue base) cancer. If so, you may be able to take part in a research study testing markers to determine who may be appropriate for less aggressive therapy and markers to determine if recurrent tumors can be detected earlier.

To see whether a blood and urine test can be used to detect circulating tumor HPV DNA in women with cervical cancer. The hope is to be able to use this test in the future to help find cervical cancer earlier and detect any new cancer in people previously treatment for it.

Two types of radiation treatment are routinely used for prostate cancer: photon (X-ray )therapy and proton therapy. The purpose of this study is to directly compare the two therapies to determine which one has better disease control and fewer patient-reported and physician-reported side effects.

Burnout within the health care setting is a known problem. The COVID-19 pandemic has lead to dramatic changes in the health care workplace and may lead to worsening burnout. This study aims to identify the most worrisome workplace stressors at UNC across departments so that changes can be made to address burnout.

The goal of this study is to see if it is feasible to use electronic questionnaires to measure patient related outcomes before, during, and after radiation for gynecologic cancer in a high-volume radiation oncology clinic.

This is a non-interventional, observational study to collect data on survival, quality of life, and other follow-up information on patients who receive GammaTile therapy.

The purpose of this study is to evaluate the usability of current SAFE Employee incident report and inform the design of an enhanced version of the report.