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Research Studies

UNC-Chapel Hill Department of Urology

12 studies match your search
Not currently enrolling

ImmunityBio, Inc./ "A Multiceter Clinical Trial of ntravesical Bacillus Calmette-Guerin (BCG) in Combination with BCG Unresponsice High Grade Non-Muscle Invasive Bladder Cancer

You are being asked to participate in this research study because you have been diagnosed with a type of non-muscle invasive bladder cancer (NMIBC) and when you were previously treated with Bacillus Calmette-Guerin (BCG), a standard therapy for NMIBC, you had a limited or no response to the treatment (BCG unresponsive). This means that your disease either did not improve on treatment or progressed following at least one course of treatment with BCG, or it returned within 12 months after receiving at least two courses of BCG treatment. The current standard of care for BCG unresponsive bladder cancer is for the surgeon to offer removal of your bladder (cystectomy), which may reduce the risk of your disease progressing to invasion of the muscle layer of your bladder but may be associated with complications, morbidity and decreased quality of life.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Bladder)
Open

Prostate Cancer surveillance and Green Tea

Have you been diagnosed with prostate cancer but just being closely monitored? If you have prostate cancer but are not being treated or plans to have treated in near future, you may be able to participate in a trial to find out if a supplement made of green tea can slow your prostate cancer from growing.

Age & Gender
  • 21 years ~ 99 years
  • Male
Study Interest
  • Cancer (Prostate)
Not currently enrolling

PRIORITY

Patients with previous negative prostate biopsy, but still considered at risk for prostate cancer may be eligible to take part in a study where they will have have further tests performed along with their scheduled repeat prostate biopsy. These research performed tests are being evaluated in hopes of making more accurate diagnosis and reduce the need for repeat biopsies.

Age & Gender
  • 40 years ~ 85 years
  • Male
Study Interest
  • Men's Health
By physician referral or invitation only

Assessment of electronic cigarette harm perception and utility as a smoking cessation aid among bladder cancer survivors

o assess the perception of harm of electronic nicotine delivery systems, such as the e-cigarette, from bladder cancer patients.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Urinary and Bladder
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Latinx Adaptation of a Hypospadias Decision Aid

The purpose of this study is to culturally and linguistically adapt a decision aid website for Lantinx populations. This decision aid website was created to assist parents and providers in making a shared decision about surgery to repair hypospadias.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Parents of Children
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Measurement of Patient Preferences with Bladder Cancer

Develop a device to measure patient preferences in the treatment of bladder cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Bladder)
  • Opinions and Perceptions
  • Urinary and Bladder
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Evaluating the sexual quality of life of Kidney Stone patients

To better understand and address kidney stone-forming patients' sexual concerns

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Sexual and/or Reproductive Health
  • Urinary and Bladder
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Prostate cancer care with or without gene testing

This project is a randomized clinical trial (study that randomly assigns participants to one arm to fairly understand outcomes) that aims to assess if information from gene expression classifier (GEC) testing is helpful for both patients and their doctors in the management of care for newly diagnosed prostate cancer patients.

Age & Gender
  • 18 years ~ 99 years
  • Male, Gender Inclusive
Study Interest
  • Cancer (Prostate)
  • Men's Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Bladder cancer study with EG-70

This study will evaluate the safety and tolerability of EG 70, a gene therapy, which is given inside the bladder, and its effectiveness on eliminating bladder tumors in patients with NMIBC who have failed BCG therapy and have been recommended to have their bladder removed. Giving the study drug inside the bladder is to expose cells in the lining of the bladder, including your cancerous cells, to genes that may cause an immune response inside the bladder and kill the tumor cells.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Bladder)
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Shorter Stent Duration After Ureteroscopy

The rationale for this study is to determine if there is a difference in symptoms or complications among patients undergoing uncomplicated ureteroscopy for stone removal with shorter indwelling stent duration. Curently there are only a few small studies exploring the optimal duration of stent placement after stent placement and no multicenter randomized control trials.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
  • Surgery and post-operative healing
Visit Location
100% Remote (online, phone, text)
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