• Home
  • Search Results

Research Studies

UNC-Chapel Hill Lineberger Comprehensive Cancer Center

241 studies match your search
Open

UNC Pleural Fluid Registry

Have you been diagnosed with pleural fluid, and have been referred for a pleural fluid drainage? If so, you may be able to participate in a research registry to help us learn more about lung cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lung)
  • Lungs and Breathing
Visit Location
100% Remote (online, phone, text)

Symptom Monitoring for Patients with Hospital-Diagnosed Advanced Lung Cancer

The purpose of this study is to understand how monitoring symptoms at home after lung cancer diagnosis could impact quality of care and the likelihood of returning to the hospital. This study will also help us understand whether symptom monitoring in patients with advanced lung cancer is helpful for patients and the clinical teams who care for them.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Behavior
  • Cancer (Lung)
  • Lungs and Breathing
Open

Prostate Cancer Outcomes: An International Registry to Improve Outcomes in Men with Advanced Prostate Cancer (IRONMAN)

Have you been diagnosed with Advanced Prostate Cancer? If so, you may be able to take part in an International Registry for Men.

Age & Gender
  • 21 years ~ 99 years
  • Male
Study Interest
  • Cancer (Prostate)
  • Urinary and Bladder
  • Men's Health
Open

T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-positive breast cancer

Have you been diagnosed with HER-2 positive breast cancer and have already received treatment with chemotherapy followed by surgery? Was your breast cancer still present at time of surgery and removed? If so you may be eligible for a trial to see if a combination of T-DM1 with tucatinib is better than receiving T-DM1 alone at preventing your cancer from returning.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Breast)
  • Sexual and/or Reproductive Health
  • Women's Health
Open

TBCRC-047-Avelumab With Binimetinib, Utomilumab, or Anti-OX40 Antibody PF-04518600 in Treating Triple Negative Breast Cancer (InCITe)

Have you ever been diagnosed with metastatic triple negative breast cancer and received 2 or less lines of chemotherapy for your metastatic disease? If so you may be eligible for a trial to evaluate different treatment combination with avelumab for your metastatic breast cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Breast)
Open

Niraparib in Combination With Trastuzumab in Metastatic HER2+ Breast Cancer

Have you ever been diagnosed with HER2 positive metastatic breast cancer and had disease progression after receiving at least one type of therapy? If so you may be eligible for a clinical trial that tests niraparib in combination with trastuzumab.

Age & Gender
  • 18 years ~ 99 years
  • Female
Study Interest
  • Cancer (Breast)
Open

Cognitive and Brain Functioning after Treatment for Breast Cancer

Have you recently been diagnosed with breast cancer but have not yet started treatment (other than surgery)? You may be able to take part in the UNC CogMAP study. In this study, we want to learn more about cognitive and brain function before and after cancer treatment. This will help us to better understand risk factors for experiencing cognitive difficulties during and after treatment.

Age & Gender
  • 18 years ~ 75 years
  • Female
Study Interest
  • Aging
  • Brain, Head, Nervous System
  • Immune System/Infections
  • and 4 more
Open

Ph3 Randomized, Double-blinded, Placebo with Atezolizumab and Bevacizumab

Have you been diagnosed with locally advanced or metastatic hepatocellular carcinoma? If so, you may be a good fit to help us learn if adding tiragolumab to standard therapy could help you and others with your condition

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Kidney)

Melanoma Research Study

In this study, we want to learn if a combination of two drugs (fianlimab and cemiplimab) is an effective treatment compared to a drug called pembrolizumab for people who have had melanoma removal surgery but are still at high risk for recurrence of the disease.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Melanoma)

A Study of ACR-368 in Ovarian Carcinoma, Endometrial Adenocarcinoma, and Urothelial Carcinoma

This is a Phase 1b/2, multicenter, open-label, basket study evaluating ACR-368, an adenosine triphosphate-competitive selective inhibitor of checkpoint kinase (CHK)1 and CHK2, as monotherapy and in combination with ultralow-dose gemcitabine (ULDG), in the treatment of subjects with histologically confirmed, locally advanced or metastatic, recurrent platinum-resistant high-grade ovarian or endometrial adenocarcinoma, or platinum-resistant urothelial carcinoma (hereafter referred to as ovarian, endometrial, and urothelial, respectively).

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Other Cancers, Uterine (endometrial), Ovarian)
  • Urinary and Bladder
  • Women's Health
Research for Me logo

Copyright © 2013-2022 The NC TraCS Institute, the integrated home of the NIH Clinical and Translational Science Awards (CTSA) Program at UNC-CH.  This website is made possible by CTSA Grant UL1TR002489 and the National Center for Advancing Translational Sciences.

Questions?

  • This email address is being protected from spambots. You need JavaScript enabled to view it.
logo for the North Carolina Translational and Clinical Sciences Institute
logo for UNC Health
logo for UNC School of Medicine
logo for UNC Research