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UNC-Chapel Hill Lineberger Comprehensive Cancer Center

241 studies match your search
Not currently enrolling

Patterns of Natural Aging Study

We are doing a study to learn more about how people age. We want to learn more about the patterns of natural aging and the link between the small changes your body makes (biomarkers) and quality of life.

Age & Gender
  • 45 years ~ 85 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Healthy Volunteer or General Population
  • Wellness and Lifestyle

Prostate Cancer Treatment Decisions for Black Patients

The purpose of this research study is to better understand, from the perspective of Black patients, whether telemedicine visits make prostate cancer decision making easier or harder. The COVID-19 pandemic made it more difficult for patients to see their doctors, but care could continue by having appointments via a computer or phone, which many prostate cancer doctors used. Whether in person or remote, successfully choosing a treatment for prostate cancer often uses shared decision making (SDM), the process where doctors and patients work together to make decisions that match what matters to patients, but it is unknown whether virtual appointments make discussions better or worse. Other studies have shown that Black patients may be less satisfied with their treatment choices than non-Black patients. Therefore, it is important that we understand how to improve the same quality of care for Black patients.

Age & Gender
  • 18 years ~ 99 years
  • Male, Gender Inclusive
Study Interest
  • Cancer (Prostate)
  • Opinions and Perceptions
  • COVID-19
  • and 2 more
Visit Location
100% Remote (online, phone, text)
Not currently enrolling

COVID-19 Information Access Survey Study

In this study, we want to learn how people access information about COVID-19. We also want to learn how people are responding to the pandemic. The results of this study will help us to promote more effective ways to communicate information.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
  • COVID-19
Visit Location
100% Remote (online, phone, text)
Open

Testing CC-486 (Oral Azacitidine) Plus the Standard Drug Therapy in Patients 75 Years or Older With Newly Diagnosed Diffuse Large B Cell Lymphoma

Have you been recently diagnosed with Diffuse Large B Cell Lymphoma? Are you over 75 years of age? If so, you may be able to take part in a research study looking at the safety of giving a new study drug CC-486 (oral azacitidine) in addition to the standard chemotherapy drug combination used to treat this disease.

Age & Gender
  • 75 years ~ 99 years
  • Male, Female
Study Interest
  • Aging
  • Cancer (Lymphoma)
Not currently enrolling

Testing Early Treatment for Patients With High-Risk CLL or SLL

To evaluate whether early drug treatment extends overall survival compared with delayed drug treatment with high-risk (chronic lymphocytic leukemia [CLL] newly diagnosed asymptomatic CLL/SLL patients.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Leukemia, Lymphoma)
  • Chronic Conditions
  • Immune System/Infections
Open

Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma

Have you been diagnosed with primary central nervous system (CNS) lymphoma? If so you may be able to take part in a research study looking at whether using the study drugs lenalidomide, and nivolumab can be safely used in addition to the standard treatment of primary CNS lymphoma, and which dose is the most adequate when they are used together.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lymphoma)

Study of Acalabrutinib in Relapsed/Refractory CNS Lymphomas

The purpose of this study is to test whether giving the study drug acalabrutinib is safe and could help control B-cell Non-Hodgkin CNS lymphoma that have not gone away, or have come back, after the first round of treatment.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lymphoma)
Not currently enrolling

Health-E from Home: Evaluation of an intervention using a small behavior changes approach to promote health and weight management

The purpose of this study is to evaluate participation in an 8-week community-based, online program for adults that will help them make small changes to their diet, physical activity, and other behaviors to help promote their health or manage their weight. We are interested in who will participate, how much participants will use the program, how many participants are interested in preventing weight gain or losing weight, and how the program will affect eating, physical activity, and stress. This program is based on previous research on approaches the researchers have studied to help people make small changes to their behavior and is being offered in response to an identified need to offer health promotion resources during the COVID-19 pandemic

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Behavior
  • Healthy Volunteer or General Population
  • Wellness and Lifestyle
  • and 3 more
Visit Location
100% Remote (online, phone, text)

Pancreatic cyst follow-up study

There are currently two common follow-up plans for patients that discover they have a pancreatic cyst. One plan has the patient seen more frequently and the other less frequently. This study attempts to answer the question of which approach is better by randomly assigning each participant to a plan and following them for 5 years.

Age & Gender
  • 50 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Pancreatic)

The HealthScore Health Coaching Program

The purpose of this research study is to deliver 6 months of 1:1 health coaching to cancer patients being treated at UNC Cancer Hospital. This program hopes to improve patient's self-confidence and satisfaction with how they feel and what they are able to do day-to-day. This includes exercising, support for healthy eating, emotional and social needs. Health coaching means you will receive weekly phone calls and emails from a trained coach.

Age & Gender
  • 15 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Behavior
  • Chronic Conditions
  • Mental and Emotional Health
  • and 4 more
Visit Location
100% Remote (online, phone, text)
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