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UNC-Chapel Hill Lineberger Comprehensive Cancer Center

270 studies match your search
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CD30 CAR-T cells for Hodgkin's/Non-Hodgkin's Lymphom

Do you have lymphoma that has come back, or did not get better with the last treatment you were given? If so, you might able to participate in a study to see if the study team can make modified T cells that are able to fight and kill the lymphoma cells.

Age & Gender
  • 3 years ~ 17 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lymphoma)
Visit Location
Open

Collection of Tissue, Blood, Urine, Hair, and Saliva for Research Related to Patients with Genitourinary Malignancies

Do you have bladder, kidney, prostate, or another genitourinary cancer diagnosis? If so, you may be able to take part in a research study collecting specimens (e.g., blood, urine, saliva, tissue) during your already scheduled appointments. Collecting these specimens may help researchers develop new ways to detect cancer earlier or to more effectively treat cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Bladder, Kidney, Prostate)
Not currently enrolling

STRIKE

To compare disease-free survival (DFS) as assessed by the investigator for high-risk renal cell carcinoma patients treated with adjuvant pembrolizumab and tivozanib versus those receiving pembrolizumab alone.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Kidney, Other Cancers)
  • Kidneys and Liver
  • Urinary and Bladder
Visit Location
100% Remote (online, phone, text)
Not currently enrolling

Intravesical BCG vs GEMDOCE in NMIBC (BRIDGE)

This study is being done to answer the following question: Can we lower the chance of your bladder cancer growing or spreading by using one type of chemotherapy instilled in the bladder, Gemcitabine and Docetaxel, instead of the usual BCG therapy? We are doing this study because we want to find out if this approach is better or worse than the usual approach for your bladder cancer. The usual approach is defined as care most people get for bladder cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Bladder)
Visit Location
100% Remote (online, phone, text)

SONOBIRD (for SONOcloud for Bbb opening In gbm Recurrent Disease)

The purpose of this study is to evaluate and compare the survival outcome of patients with first recurrence of GBM undergoing surgical debulking/resection followed by either implantation of the SC9 device and repeat BBB opening in association with carboplatin chemotherapy or standard of care second line chemotherapy with either lomustine or temozolomide (per best physician's choice and best practice).

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Brain and Other Nervous System)
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Improving Cervical Cancer Screening for Women Living with HIV - Testing HPV Self-Collection in Clinics and Communities in Uganda

The purpose of this study is to assess how the use of community health-workers for human papillomavirus (HPV) testing influences the number of women living with HIV who get screened for cervical cancer.

Age & Gender
  • 18 years ~ 99 years
  • Female
Study Interest
  • Cancer (Cervical)
  • HIV/AIDS
  • Sexual and/or Reproductive Health
  • Women's Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Evaluating mPATH-Cloud, a digital decision aid and navigation tool to support CRC screening

We are implementing a digital health intervention, mPATH-Cloud, in one community health center. Patients who receive a link to the mPATH-Cloud website will be able to view a video designed to help them choose the colorectal cancer (CRC) screening test that is best for them. Patients who select colonoscopy will receive a referral from their primary care provider. Patients who do not select colonoscopy will receive a FIT in the mail. We will assess the feasibility and effectiveness of implementing mPATH-Cloud in combination with mailed FIT outreach for increasing CRC screening among community health center patients.

Age & Gender
  • 45 years ~ 73 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Colorectal)
  • Healthy Volunteer or General Population
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Liver Surgery Weight Tracking Study

The purpose of this research study is to monitor how well patients with fatty liver disease can follow clinician-recommended diet and exercise before their liver surgery. Our goal is to understand patient adherence to weight-related goals, weight loss, physical activity, and improved liver health. You are being asked to be in the study because you are a patient with fatty liver disease planning to have liver surgery.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Colorectal, Liver)
  • Kidneys and Liver
  • Wellness and Lifestyle
  • and 3 more
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

CPC health behaviors

This is a research study to better understand people's health behaviors.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
Visit Location
100% Remote (online, phone, text)

Addressing Cancer-Related Financial Toxicity in Rural Oncology Care Settings

The purpose of this study is to learn how having specific help over a period of time (financial navigation) can help reduce your distress related to the cost of cancer. You will complete a survey to see if you have financial distress. If you have financial distress, you will then fill out a few more surveys and be asked more details about your current financial situation to determine what programs could be helpful for you. The surveys can be completed in person, by email, or over the phone. The navigator can help you complete the surveys if needed. After that, depending on your needs, you will have 1-6 appointments with the financial navigator over a period of 2 weeks -4 months. Risks to you are small due to the educational nature of this study. They may include mild emotional distress while talking about your cancer and financial experiences. Benefits

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Bladder, Brain and Other Nervous System, Breast, and 18 more)
Visit Location
100% Remote (online, phone, text)
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