The main purpose of this study is to determine how much MRTX849 can safely be administered to people. This will include looking at what side effects occur and how often they occur.

The purpose of this study is to learn what women with HIV think about cervical cancer screening. We also want to talk about the idea of using HPV self-collection (where women collect their own sample) instead of going to the clinic for testing. This information will help us see if self- collection can help more women with HIV get screened for cervical cancer.

The purpose of this study is to create a registry that will collect clinical data from participants attending UNC Hospitals who may present with metastatic cancer and are evaluated to receive radiation therapy. We hope to create a registry that future studies can pull from to study the impacts of radiation therapy on patient cancer outcomes.

We want to learn more about how patients who have small renal masses make treatment decision and about what kinds of features they value in the tests that we use to work up this condition.

The purpose of this study is to assess how the use of community health-workers for human papillomavirus (HPV) testing influences the number of women living with HIV who get screened for cervical cancer.

To initiate and evaluate a multilevel navigation intervention to promote lung cancer screening among Black/African Americans

The main goal of this project is to create an interactive online version of the Let's Talk program and test it with patients who have Lynch syndrome to see if it works well in a medical setting.

Pleuropulmonary Blastoma (PPB) is a rare lung tumor in young children that can grow in stages from less serious (Type I) to more dangerous (Type III). This study will test how well a drug combo: vincristine, topotecan, and cyclophosphamide (VTC) works for serious types (Type II and III) and help decide which patients with less serious tumors (Type I and Type Ir (regressed) PPB ) need chemotherapy after surgery. Researchers will also study the biology of the tumor to learn more about it.

To evaluate whether different biomarkers can stratify patients with newly diagnosed GBM that have progressive enhancement within 12 weeks post-XRT into risk groups based on overall survival.

Develop a set of effective little cigar and cigarillo warning statements.