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UNC-Chapel Hill Lineberger Comprehensive Cancer Center

270 studies match your search
By physician referral or invitation only

Brain slice explants to predict drug response in brain tumors

You are being asked to participate in this research study because you have a type of tumor called a Central Nervous System (CNS) tumor, and you are scheduled to have surgery to remove this tumor. The study team wants to use left-over tumor samples from this surgery to study your tumor and test new ways to fight it.

Age & Gender
  • 0 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Brain and Other Nervous System)
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Evaluating a Decision Support Tool for Adults Seen in Hematology/Oncology Clinics

This is a study evaluating whether the use of an electronic web-based tool containing surveys could support patients and doctors make better treatment decisions together. New patients, 60 years or older, will be randomized to either receive the tool or not. Surveys will be collected from patients about their experience in making treatment decisions to evaluate whether the tool was beneficial.

Age & Gender
  • 60 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Leukemia)
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Artificial Intelligence Prediction Tool in NMIBC

The purpose of this study is to develop and validate an Artificial intelligence (AI)-based tissue sample analysis tool that can predict response & progression rates to chemotherapy in intermediate-risk (IR) and high-risk (HR) Non-muscle invasive bladder cancer (NMIBC) patients. This study will use AI-based tissue sample analysis as a possible tool to help predict which patients are at high-risk for cancer recurrence and progression after surgery and chemotherapy treatment. Specimens will be obtained for each patient before treatment and at the 12, 24, & 36 month follow-up to be analyzed using the AI-based tool.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Bladder)
Visit Location
100% Remote (online, phone, text)

Little Cigar and Cigarillo Warnings to Reduce Tobacco-Related Cancers and Disease - Aim 2 RCT

The proposed study will fill critical gaps regarding which characteristics make LCC warning labels most effective and provide needed evidence on how LCC warnings influence LCC behavioral intentions. Our overarching goal is to develop effective LCC warnings that reduce cancer and other health risks.

Age & Gender
  • 21 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
  • Substance Use (tobacco, alcohol, opioids, etc)
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

MTM-Kids

The study purpose is to find out if (a) it's possible to deliver healthy frozen meals to homes of children receiving chemotherapy, and (b) the meals are acceptable to the children and their families.

Age & Gender
  • 12 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Pediatric Cancers)
Visit Location
100% Remote (online, phone, text)

Racial Disparities and Barriers in the Delivery of Guideline-Recommended Care for Metastatic Prostate Cancer

Black men are diagnosed with prostate cancer more often than white men, and more commonly die from this disease. Care for advanced prostate cancer has improved a great deal over the past ten years, but these differences have continued. In order to improve equity in cancer care, we want to determine who is not getting the highest quality of care and whether race is associated with differences in care. Our study will ask Black and White men about their experiences with cancer care - if they trusted their doctors, how well their doctors communicated with them, and if they were satisfied with the care they received. We will ask about the challenges they experienced in receiving care, and what might have helped them get better care. We will use these results to design a better way to deliver care.

Age & Gender
  • 18 years ~ 99 years
  • Male
Study Interest
  • Cancer (Prostate)
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Identifying facilitators and barriers to implementing dyadic survivorship interventions in clinical care

The main objective is to glean stakeholders' perspectives about implementing and disseminating an intervention for Black women with breast cancer and their female support people into clinical care.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Breast)
  • Women's Health
  • UNC or UNC Health employees
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Vaping prevention video ads study

We are studying how young people respond to vaping prevention video ads. We are inviting people aged 13-20 to participate in this research. Participants will watch some short videos about vaping and answer a survey. The whole process will take approximately 20 minutes. Feedback will help improve future vaping prevention efforts.

Age & Gender
  • 13 years ~ 20 years
  • Male, Female, Gender Inclusive
Study Interest
  • Behavior
  • Healthy Volunteer or General Population
  • Minority Health
  • and 6 more
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

VisR Ultrasound for Non-Invasive Evaluation of Anisotropy in Breast Cancer Patients

This study will investigate how mechanical properties of breast tissue, such as stiffness, viscosity, and anisotropy, are related to breast tumor malignancy and response to chemotherapy. The study uses ultrasound imaging to measure these mechanical properties non-invasively in human subjects.

Age & Gender
  • 20 years ~ 90 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Breast)
  • Women's Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

IOV-EAP-402/Expanded Access Program of AMTAGVI that is Out of Specification for Commercial Release

To provide AMTAGVI per United States Prescribing Information (USPI) to patients.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Melanoma)
Visit Location
100% Remote (online, phone, text)
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