Have you been newly diagnosed with or suspected of having either acute myelogenous leukemia or high risk myeloid neoplasm? Are you looking for other treatment options? In this study, depending on the specific type of leukemia you have, our study team will determine the different treatment options that we can provide to you.

Do you have AML and have received previous chemotherapy or radiation treatment? Are you looking for another treatment option? In this study, we want to see if by adding Pomalidomide a study drug, what dose is the most effective at treating your AML?

This research study is for people with essential thrombocythemia (ET) who need to start therapy to reduce blood counts or your currently therapy is not controlling your ET. In this study, we want to find out if a new drug can help normalize your blood count.

Have you been diagnosed with Leukemia and are looking for another treatment option? In this study we are looking to see if the study drug DSP-5336 can help control Leukemia or achieve remission.

Do you have cancer? Are you about to start immunotherapy? You may be able to participate in a research study to help answer many questions that still exist about immunotherapy like - Who is more likely to get side effects? What treatments will help control the side effects but let patients continue their cancer treatment? What factors can affect the type of side effects patients have (type of cancer or immunotherapy? previous chemo or radiation? existing autoimmune diseases?, etc.) and more.

Are you living with Metastatic or Advanced Cancer? Are you interested in having a personal health coach to help you set healthy lifestyle goals? Your personal health coach would prescribe cardio and strength training exercises, help you monitor symptoms, and navigate you to supportive care. If you have cancer and are receiving care at UNC Cancer Center, you may be able to participate.

Have you been diagnosed with Acute Lymphoblastic Leukemia? Has your leukemia come back or didn't get better after your last treatment? If so, you may be able to take part in a research study to learn more about the safety of modifying your own immune cells to treat your leukemia.

The purpose of this study is to create a registry that will collect clinical data from participants attending UNC Hospitals who may present with metastatic cancer and are evaluated to receive radiation therapy. We hope to create a registry that future studies can pull from to study the impacts of radiation therapy on patient cancer outcomes.

Assess the safety and tolerability of ZN-d5 and ZN-c3 when administered in combination and ZN-c3 monotherapy, in subjects with AML. Determine the MTD and RP2D for ZN-d5 and ZN-c3 when administered in combination to subjects with AML.

To evaluate whether early drug treatment extends overall survival compared with delayed drug treatment with high-risk (chronic lymphocytic leukemia [CLL] newly diagnosed asymptomatic CLL/SLL patients.