Cancer is the leading cause of death in the Hispanic population in the U.S. Our study focuses on collecting information to build a cancer registry from a diverse Hispanic population to identify specific cultural and demographic details that will allow us to determine which attribute carries a higher risk of a poor outcome. We will also be utilizing a set of questionnaires and surveys that evaluate the health and functionality of older adults thoroughly and efficiently. These surveys provide a wealth of prognostic data and have been shown to detect deficits even in younger patients. Although the information we hope to collect is of considerable value, we must first examine whether our approach to consenting patients and having them complete these questionnaires is feasible. We anticipate that the findings from our study will provide valuable insights on Hispanic adults with cancer as a unique and growing patient population in the U.S.

To evaluate whether early drug treatment extends overall survival compared with delayed drug treatment with high-risk (chronic lymphocytic leukemia [CLL] newly diagnosed asymptomatic CLL/SLL patients.

To assess the efficacy of itolizumab versus placebo as initial therapy for aGVHD in combination with corticosteroids in achieving early disease response.

The purpose of this study is to develop a prospective longitudinal cohort/registry of lymphoma patients in Malawi to address a lack of prospective longitudinal data related to lymphoma in sub-Saharan Africa, and to serve as a foundation for developing optimal treatment strategies in this challenging environment.

The purpose of this study is to learn how having specific help over a period of time (financial navigation) can help reduce your distress related to the cost of cancer. You will complete a survey to see if you have financial distress. If you have financial distress, you will then fill out a few more surveys and be asked more details about your current financial situation to determine what programs could be helpful for you. The surveys can be completed in person, by email, or over the phone. The navigator can help you complete the surveys if needed. After that, depending on your needs, you will have 1-6 appointments with the financial navigator over a period of 2 weeks -4 months. Risks to you are small due to the educational nature of this study. They may include mild emotional distress while talking about your cancer and financial experiences. Benefits

The purpose of this study is to create a registry that will collect clinical data from participants attending UNC Hospitals who may present with metastatic cancer and are evaluated to receive radiation therapy. We hope to create a registry that future studies can pull from to study the impacts of radiation therapy on patient cancer outcomes.