The purpose of this research study is to learn if and how non-invasive brain stimulation influences motivation problems in Parkinson's disease. Men and women aged 55-80 years with Parkinson's disease for at least 5 years can join the study. There are three study visits. Participation will involve answering questions, doing exercises where you squeeze a joystick to earn "rewards", recording of your brain activity, and receiving transcranial magnetic stimulation (TMS).

A study to investigate the efficacy and safety of efgartigimod PH20 SC in adult participants with active idiopathic inflammatory myopathy

The purpose of the HEALEY ALS Platform Trial is to develop and administer various clinical trials under different regimens with ALS to provide multiple treatment options for patients with ALS.

This study aims to understand how individuals with stroke participate in the community in Southwestern China. Also, this study explores the barriers and facilitators of participating in the community for individuals with stroke in Southwestern China.

This clinical trial aims to understand how well ALXN-C5IT works over a long time. We want to see if it can prevent relapses and help with disability, walking, and vision. We also want to know how patients feel about their health while using ALXN-C5IT.

The purpose of this study is to evaluate the efficacy of sodium thiosulfate (STS) infusion administered during cisplatin-containing chemotherapy cycles in reducing hearing loss in children with newly-diagnosed average-risk medulloblastoma.

The purpose of this study is to determine if memantine, a medication commonly used for dementia, may lessen cognitive changes that may occur during treatment for breast cancer.

The purpose of this study is to determine the efficacy of the app outSMARTPD in determining a user's percent likelihood of having Parkinson's Disease through the studies and tests present in the app. The goal of the app is to determine if it is an effective tool for elderly populations that may have neurodegenerative disease, to help existing patients monitor their symptoms, and to help doctors and neurologists with patients that may have a Parkinsonian patient.

The purpose of the study is to establish a Clinical Cohort (group) of research participants to examine normal cognition, mild cognitive impairment and Alzheimer's disease and related disorders (ADRD) as people get older. We will be measuring changes in your memory and the way you process information as you age. As part of the study, you will be asked to participate in yearly evaluations of your memory and health. You will have brain imagining done by Magnetic Resonance Imaging (MRI), a lumbar puncture and blood will be drawn at some visits. Also, as part of this research you must designate a "project partner." This should be someone who is familiar with your health and will be able to provide information about your health and wellbeing as appropriate.

The purpose of this project is to create and distribute a survey with the intent to collect data about the amount and quality of training critical care physicians receive regarding brain death (i.e., death by neurologic criteria). We are doing because teaching physicians about brain death is not standardized and the subject is complex.