The purpose of this study is to explore etentamig (ABBV-383) and its safety and tolerability as a monotherapy or combined with other anti-myeloma agents. This study aims to determine the safest dose of etentamig and if it produces meaningful anti-myeloma activity for participant with multiple myeloma (MM).

The study identifies terminal time of different trips, links them with spatial and demographic characteristics, which will help urban policy formulation.

This is a two-part training series designed to inform community organization leaders about what evidence is and how they can use it, what evidence-based interventions are and where they can find them, and how to select evidence-based interventions that work for them and their community.

We are focused on identifying strategies to improve maternal healthcare at a for American Indian birthing people.

To evaluate the efficacy of ION582 in participants with Angelman syndrome (AS) receiving ION582 vs Placebo as measured through expressive communication as well as measured through functional domains, including overall symptoms of disease severity, cognition, communication, sleep, motor functioning, and daily living skills.

The purpose of this research study is to see how school leaders and teachers interpret the NC science of reading laws and make curricular and instructional decisions.

This study explores the willingness of off-reservation Muscogee (Creek) Nation citizens to engage in digital cultural connection and futurity. It aims to understand how online engagement can foster stronger cultural ties and enhance the connectivity and well-being of all Muscogee people. The study will be using a mix of online survey data from off-reservation citizens and in-person interviews of citizens that reside on the reservation to find out current resources offered to Muscogee citizens, gaps in communication, and where there is a need/want for future resources.

This project is studying the effect of pediatric care coordination on the behavioral health of children and parents.

Systematic reviews (SRs) of healthcare interventions should identify patient safety concerns; however, many SRs are designed to assess benefits, and preliminary evidence suggests that conclusions about harms in SRs might not be trustworthy. Using >19,000 SRs of drugs for which we have full texts (including >4,000 overlapping reviews), and using innovative methods for analysis (e.g., natural language processing), we will examine whether information about safety in SRs is consistent, whether SRs address safety concerns identified using real-world evidence, and whether SRs are consistent with safety information on drug labels. Based on best evidence, including findings from this study, we will develop contemporary guidance for synthesizing and reporting safety information in SRs.

The purpose of this study is to estimate the number of Lyme and other tick-borne disease cases occurring in Biltmore Forest.