This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.

We are performing a clinical study to determine the optimal frequency for medications for infected pleural fluid, referred to as intrapleural enzyme therapy (IET). Participants will either receive once daily IET or twice daily IET. We hypothesize that once daily IET will be non-inferior to twice daily IET.

The primary purpose of this work is to engage a broad group of stakeholders to implement a patient-centered approach to the de-adoption of self-monitored blood glucose among non-insulin-treated patients with Type two Diabetes Mellitus. We will evaluate the effectiveness of Rethink the Strip finalize and package it for nationwide dissemination.

The purpose of this research study is to determine the cause and mechanism of alpha-gal mammalian meat allergy. Alpha-gal is a novel food allergy that we have only come to recognize in recent years. It seems to preferentially affect people who reside in certain geographic areas, with the southeastern US (including North Carolina) being one.

We want to empower communities to support Veterans and their families across all Vital Conditions. Veterans are a high risk group for mental illness and we want to prevent mental health crises by highlighting community capacity and enhancing strategic access to resources.

The purpose of this study is to determine which new magnetic resonance sequences provide better, faster and more useful information. A sequence is a distinct method of obtaining magnetic resonance (MR) images. A magnetic resonance imaging (MRI) exam is made up of many different imaging sequences. These new sequences will be implemented on either on a 3 Tesla (3T) MR system, a 7 Tesla (7T) MR system (single- or multi- transmit), or both. Since the signal-to-noise ratio for MR images is highly dependent on the magnetic field strength, the anticipated signal-to-noise will be 7T greater than 3T and 3T greater than 1.5T systems. The 3T MR system is FDA approved whereas the 7T system is not FDA approved, but is built to the same standards as other FDA approved scanners. In addition, the FDA has approved magnetic field strength up to 8T for human imaging. Participants will be told ahead

We are exploring the relationship between participation in the FIT Program with health outcomes, recidivism, and healthcare utilization for people who are coming out of incarceration and who have chronic illnesses.

The primary endpoint for this study is subjects achieving either a decrease in Urgency Numeric Rating Scale (NRS) score of ≥ 2 points, or a decrease in score of ≥ 30%, at 12 weeks. Success is defined as ≥ 50% of enrolled subjects meeting the primary endpoint.

The ASPIRE trial aims to study anticoagulant medications in patients who have had an intracerebral hemorrhage (bleeding in the brain) who also have atrial fibrillation (irregular heartbeats). Participants who agree to study participation will receive either Aspirin or Apixaban and followed for 12-36 months to see if they have any other strokes, and follow their general recovery after stroke.

To generate information on the undergraduate experience at the University of North Carolina at Chapel Hill from currently enrolled students. This survey is processed every other year.