The purpose of this research study is to see how use of genetic testing to help doctors with choosing blood thinning medication after a heart procedure called an angioplasty (also called percutaneous coronary intervention or PCI) affects your risk of having a heart attack, stroke, death or bleeding. Some doctors use genetic testing to help decide which blood thinner to prescribe for a patient. By doing the study, the investigators will be able to look at clinical outcomes (heart attacks, stroke, death, bleeding) after genetic testing and prescribing of blood thinning medications for patients with different backgrounds and medical histories. They will also look for new genes that affect how blood thinners work.
Students in advanced academic programming, such as that provided in Early College High Schools (ECHSs), may experience stress that interferes with their academic success. Although ECHSs provide many supports to students, there is a need for additional programming to support students' social-emotional development and stress resilience. This study involves further developing, refining, implementing, and testing a multi-tiered adaptation of Be CALM (Cool, Attentive, Logical, and Mature), a mindfulness-based SEL program that aims to enhance staff and student wellbeing and SEL competencies. Mindfulness is a practice of Pressing the Pause on purpose and Tuning In to the present moment with a curious and kind attitude that has been shown to benefit social and emotional wellbeing in students. We expect that knowledge gained from this study will be used to advance understanding of how mindfulness may be helpful to ECHS students, teachers, and counselors.
This study explores the histories of racial segregation in three areas: Tulsa, Oklahoma; St. Louis County, Missouri; and, Greenwood, Mississippi. During interviews, participants will share their memories of those places as well as create maps about where it was or wasn't safe for people in their communities to travel.
The purpose of this research study is to see how displaying different types of information may help users when conducting procedural knowledge information-seeking tasks using a search interface.
To learn more about the experimental drug, ISL/LEN. This includes: Comparing ISL/LEN weekly to B/F/TAF daily and determining which of these study treatments works better for treating HIV infection. Determining how ISL/LEN and B/F/TAF affects the HIV infection in the body. Testing and learning about the safety of ISL/LEN, how well ISL/LEN is tolerated, and how long it stays in the body using physical exam, blood and urine tests, and any symptoms or problems it may create in the study.
Medical education program to improve incoming fellows' comfort and readiness before starting their first service month.
The purpose of this pilot study is to evaluate the feasibility of analyzing peer networks to understand their influence on behaviors and well-being among high school students. By identifying social connections and key influencers, the study seeks to assess the practicality of implementing strategies aimed at enhancing positive peer influence and promoting youth mental health. This pilot will provide critical insights into the viability of a larger-scale study.
This study will explore student self-regulated learning behaviors in introductory biology classes. In particular, it will collect data regarding the effectiveness of training materials and educational technology tools (the "ZenStudy" app) on improving students' ability to self-regulate their own learning and, subsequently, their achievement in the course. In the first few weeks of class enrolled students will be asked to complete a survey to verify they are over the age of 18 and if so ask for their consent to be included in the study. Consenting participants will then be randomly assigned to conditions (control students will be asked to review a video and complete a reflective task, treatment students will be invited to utilize the ZenStudy application and complete an evaluative survey). Engagement with the ZenStudy application will then be analyzed as a potential moderator of student digital course engagement and achievement.
A Phase IV, multicenter, randomized, open label trial to evaluate the effectiveness of inclisiran + usual care vs usual care alone as a tool to close care gaps within a pragmatic framework in an inclusive and underrepresented population at high risk for or diagnosed with ASCVD.
The purpose of the study is validate the first measure of disease-specific quality of life in patients diagnosed with eosinophilic gastritis (EG) or eosinophilic gastroenteritis (EGE).