The purpose of this study is to understand how your gut plays a role in how well CAR T cell therapy works. Your gut is home to bacteria, which we call the gut microbiome. The gut microbiome can send signals to your immune cells, which may impact how well and how long CAR T cell therapy will last. We can find out what type of bacteria are in your gut microbiome by studying your stool. We can understand more about the signals sent to the immune system by studying your blood. We will ask for stool and blood at the same time points throughout your treatment. We will study the identities and function of the bacteria and immune cells to understand more about how these signals work during CAR T cell treatment.
Cochlear Implantation often results in loss of any remaining hearing that may have been present prior to the surgery and the patient uses only the cochlear implant to hear. Saving the remaining hearing is important because it can allow a recipient to also utilize a hearing aid in that ear in addition to the cochlear implant, termed electro-acoustic stimulation. Thus, the goals of this study are: 1) to determine the importance of electrocochleography in helping to save remaining hearing during the surgical procedure, 2) determine the benefit that a hearing aid and cochlear implant combination of listening impacts a patient's ability to understand speech compared to the traditional condition of using the cochlear implant alone without a hearing aid.
To develop a curriculum for resident education in ultrasound for quality improvement in diagnosis, surveillance and management of multiple areas
The purpose of this study is to develop and refine an entrusable professional activities (EPA) framework that can be utilized nationwide by dental hygiene programs. EPAs will help to enhance the standardization of practice among graduating clinicians in dental hygiene. By utilizing an EPA framework this will help to bring a legitimacy to the clinicians' ability to provide appropriate patient care to their communities.
Functional Electrical Stimulation (FES) is a commonly prescribed technology for restoration of limb function and muscular rehabilitation. FES works by artificially stimulating muscle fibers to generate a contraction. However, one of the main issues with the use of FES is the rapid onset of muscle fatigue, which makes it difficult to perform long-term periodic motions such as walking. Recent research has shown methods successful at mitigating the impact of muscle fatigue using multiple electrodes. Instead of using the traditional approach of two FES pads targeting a specific muscle group, this study will use multiple electrodes and cycles the order in which the electrodes are stimulating thus targeting specific muscles within the muscle group and reducing the muscle fatigue. However, how to optimize the current through multiple electrodes is not known yet. This study will help determine the optimization of multiple electrodes for reducing fatigue.
The purpose of this research study is to learn more about patient preferences for care when undergoing treatment for drug use-associated endocarditis (DUA-IE), specifically treatment for addiction and antibiotic treatment.
The purpose of this study is to construct and test an issue engagement model that explains how individuals' social networks influence their thinking, feeling, and actions upon a social issue.
The purpose of our study is to increase our understanding of how hearing affects balance performance in older adults. This will help us know whether older adults with balance concerns should be screened for hearing loss and whether use of hearing aids may be important for improving balance and preventing falls in older adults with hearing loss.
The purpose of this research study is to learn about the structure and function of the upper GI tract epithelium (the lining of the food tube, or esophagus, stomach, and small bowel, or duodenum) in normal people and those with disease, especially those with eosinophilic esophagitis (EoE) or gastroesophageal reflux disease ("acid reflux" or GERD).
Survey to graduate program alumni 5, 8 and 15 years post-graduation to track career pathways.