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438 studies match your search

Reduced Dose of Cyclophosphamide to Prevent Graft versus Host Disease after Stem Cell Transplant

Cyclophosphamide is a chemotherapy (chemo) drug often given after a transplant to prevent GvHD. We are doing this study to see if a lower dose of cyclophosphamide after transplant is safer, but just as effective. Cyclophosphamide can prevent GvHD, but it can also make you sick and more likely to get an infection. This study will look at how well a lower dose of cyclophosphamide works to reduce these side effects, while also preventing GvHD. This study does not include any new or untested drugs. The drugs and procedures in this study are standard for transplant.

Age & Gender
  • 18 years ~ 65 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Leukemia, Lymphoma)
  • Transplant
Open

Phase I Study of CAR-T Cells Targeting the B7-H3 Antigen in Patients with Refractory Pancreatic Ductal Adenocarcinoma (PDAC)

Do you have pancreatic ductal adenocarcinoma that has come back after receiving standard therapy? If so, you may be able to participate in this gene therapy research study to learn more about using you own modified immune cells as possible treatment.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Pancreatic)

A Comparator Study of a Tasso device to traditional venous blood sampling methods for CBC in patients with leukemia, lymphoma, or other blood cell disorders

This study will evaluate the feasibility of using capillary blood samples collected with the Tasso device for analysis of CBC in diseased patients with leukemia, lymphoma, and/or other blood cell disorders.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
  • Cancer (Leukemia, Lymphoma)
Open

CAR-T Cells in the Treatment of Patients with B Cell Malignancies

Have you been diagnosed with a B cell disease that has returned after your previous treatment or is not responding to your current treatment? If so, you might be able to take part in a study to see if a new treatment is safe and can help treat people with B-cell diseases.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lymphoma)
Open

Financial Experiences of Young Adults with Cervical Cancer

Do you have cervical cancer and are confused about health insurance or paying for your healthcare? We want to hear your thoughts on what might make it easier to navigate the financial side of cancer treatment. Your participation will help us to build a program to help cervical cancer patients like you. Compensation provided.

Age & Gender
  • 18 years ~ 39 years
  • Female, Gender Inclusive
Study Interest
  • Cancer (Cervical)
  • Mental and Emotional Health
  • Opinions and Perceptions
  • Women's Health
Visit Location
100% Remote (online, phone, text)
Open

A012103-CIRB: OPTIMICE-PCR: DE-ESCALATION OF THERAPY IN EARLY-STAGE TNBC PATIENTS WHO ACHIEVE PCR AFTER NEOADJUVANT CHEMOTHERAPY WITH CHECKPOINT INHIBITOR THERAPY

Have you been diagnosed with early stage triple negative breast cancer? We are asking you to take part in this research study because you have been diagnosed with triple-negative breast cancer (TNBC) and have recently completed preoperative chemotherapy in combination with pembrolizumab, followed by breast surgery. The chemotherapy plus pembrolizumab produced a pathologic complete response (pCR), meaning that no remaining cancer was found during your breast surgery.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Breast)
Open

Breast Cancer Tumor Tissue Study

Have you been diagnosed with breast cancer? If so, you may be able to take part in a research study for the collection of tumor specimens and genomic DNA from patients with early or metastatic breast cancer.

Age & Gender
  • 18 years ~ 99 years
  • Female
Study Interest
  • Cancer (Breast)
Not currently enrolling

Feedback needed to increase risk awareness of Prostate Cancer among Black/African American males

Community-based interventions outside of North Carolina increase prostate cancer risk awareness and education among African Americans. Help us design an ideal intervention for/with communities in North Carolina. Your feedback and insight are instrumental in raising awareness and ultimately saving the lives of Black/African American men in North Carolina.

Age & Gender
  • 18 years ~ 40 years
  • Male
Study Interest
  • Cancer (Prostate)
  • Healthy Volunteer or General Population
  • Minority Health
  • Men's Health
Visit Location
100% Remote (online, phone, text)
Open

Testing Nivolumab and Ipilimumab Immunotherapy With or Without Cabozantinib

Do you Patients with have Advanced Nasopharyngeal Carcinoma that has Progressed After Platinum Treatment and Immunotherapy? If so, you may be able to participate in a research study to find out if progression-free survival of the triplet combination (CaboNivoIpi) is more favorable than the doublet (NivoIpi).

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Head and Neck)

A Phase II Study of CyBorD Plus Daratumumab for Patients with MGRS

The purpose of this study is to find out whether a combination of drugs is a safe treatment for MGRS-associated kidney disease including cast nephropathy associated with multiple myeloma. The combination of drugs in this study is cyclophosphamide, bortezomib, dexamethasone (CyBorD) with daratumumab SC. In addition, we will find out whether the study drug combination is an effective treatment for these conditions.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Multiple Myeloma)
  • Kidneys and Liver
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