The virus that causes COVID-19 disease infects many people, but only some get sick. We want to understand how COVID affects the immune system and what makes severe COVID infections different from other diseases that cause hospitalization and breathing problems. We collect samples of blood, sputum, urine, and stool from patients in the hospital to learn how COVID affects cells and molecules of the immune system.

Our project aims to document how COVID-19 is changing schools and families, and to trace the ways these changes are shaping educational inequality. In collaboration with North Carolina's Guilford County Schools, we are surveying school leaders, teachers, and parents and guardians about the academic, material, and socio-emotional resources that school communities are collectively employing in response to the pandemic. Our analyses will document school school/family collaboration during the COVID-19 crisis; investigate racial and socioeconomic inequalities in access to school services and supports; and evaluate the consequences of school supports and school/family collaboration for learning loses during the pandemic-induced interruption in regular schooling. Ultimately, we hope this project will shed light on strategies that can mitigate the pandemic's potentially disastrous consequences for educational inequality.

This is an annual UNC-Chapel Hill freshman survey as part of assessing undergraduate student development and using the results to enhance programs and services that support their success.

The purpose of this study is to create new ways to prevent heart disease that help people, specifically African-Americans, access resources to live a healthy life using a "whole person" approach to cardiovascular disease and social needs, especially in high-need communities.

To assess the safety of nonconforming lisocabtagene maraleucel in patients

This study seeks to understand how best to increase knowledge about clinical trials, best way of communicating information about clinical trials, and suggestions for improving clinical trial participation particularly among African Americans (AA).

Children diagnosed with Fragile X syndrome and Down syndrome are at substantially increased risk for developing neuropsychiatric disorders including autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD). Despite a known genetic cause for each syndrome, substantial clinical variability exists among children with both syndromes, suggesting an important role for genetic background in shaping child outcomes. We will collect behavioral and genetic data from biological parents to model the relative role of genetic background in explaining behavioral, neurobiological, and clinical variability in young children with Fragile X and Down syndrome who have been followed with brain imaging and behavioral testing since infancy.

this study is to gather data on activity and activity restrictions for women pregnant with a short cervix.

The overall purpose of this study is to evaluate the effectiveness of e-filing of Domestic Violence Protective Orders (DVPOs) in North Carolina. This phae of the study involves phone or Zoom interviews with Clerks of Court in North Carolina.

The purpose of the DETECT study is to learn more about how some breast tissue features show up on a mammogram and what these features can tell us about the potential for a breast cancer diagnosis. Your participation will help us understand how the appearance of those breast tissue features is affected by hormone levels. Our objective is to collect urine samples that we will use to measure hormone levels. We will examine how hormone levels are related to breast tissue features measured from a breast cancer screening mammogram.