The purpose of this study is to test a program to help people who have knee or hip osteoarthritis (OA). We are calling this program the "Osteoarthritis Clinic-Community CARE Model" or OA CARE. We are testing this program to see if the OA CARE program in partnership with the YMCA, helps patients with knee or hip OA manage their weight and move more.

The goal of this research is to develop fundamental knowledge in robotics and visualization, leading to a new framework, methods, and tools that enable robot operators and supervisors to take advantage of robot-collected data while in the field.

To investigate the knowledge and attitudes among NC dental hygienists towards chronic disease management.

There exists limited empirical evidence to inform the structure and content of the current NCAA exit interviews which restricts their impact on post-career health and well-being. This study hopes to bridge that gap and to understand the student-athlete transition experience including outcomes of mental, physical, social, and occupational functioning. In this aim, we are inviting you to participate in an evidence-based, survey addendum to the standard of care exit interview. A total of 120 individuals will be invited to participate in this portion of the study. A subgroup of 30 participants will be invited to participate in a follow-up interview. If you are selected for follow-up, we will reach out to you in no more than 60 days after the completion of this survey.

This study will evaluate the safety and tolerability of EG 70, a gene therapy, which is given inside the bladder, and its effectiveness on eliminating bladder tumors in patients with NMIBC who have failed BCG therapy and have been recommended to have their bladder removed. Giving the study drug inside the bladder is to expose cells in the lining of the bladder, including your cancerous cells, to genes that may cause an immune response inside the bladder and kill the tumor cells.

The purpose of this research is to assess the effectiveness and safety of cochlear implantation in children and adult patients, aged 5 years and older, with unilateral hearing loss/single-sided deafness (UHL/SSD) to support a change in indication for use.

The primary objective of the proposed project is to demonstrate the effects of limited physical facility infrastructure, diminished supplies, and gaps in Infection Prevention and Control (IPC) knowledge among Healthcare Personnel on IPC practice implementation at the health facility level to inform efficient and effective future improvement efforts.

The purpose of this study is to collected and store sinonasal tissue obtained during sinus surgery that would otherwise be discarded as medical waste. This tissue will be critical in future research projects investigating chronic sinusitis.

This study plans to learn more about two treatment approaches for chronic rhinosinusitis (CRS) in patients who have cystic fibrosis (CF) and the outcomes. The two treatment approaches this study intends to learn about are endoscopic sinus surgery (a surgical treatment used to clean out infection from your nose and sinuses) and continued medical treatment without surgery.

The purpose of this expanded access IND (compassionate use) program is to provide tecovirimat for treatment or prevention of non-variola orthopoxvirus infections (e.g., vaccinia, monkeypox, cowpox or other human virus infection identified as an orthopoxvirus) and secondary treatment of complications from replication-competent vaccinia vaccine in adults and children.