The purpose of this study is to determine which new magnetic resonance sequences provide better, faster and more useful information. A sequence is a distinct method of obtaining magnetic resonance (MR) images. A magnetic resonance imaging (MRI) exam is made up of many different imaging sequences. These new sequences will be implemented on either on a 3 Tesla (3T) MR system, a 7 Tesla (7T) MR system (single- or multi- transmit), or both. Since the signal-to-noise ratio for MR images is highly dependent on the magnetic field strength, the anticipated signal-to-noise will be 7T greater than 3T and 3T greater than 1.5T systems. The 3T MR system is FDA approved whereas the 7T system is not FDA approved, but is built to the same standards as other FDA approved scanners. In addition, the FDA has approved magnetic field strength up to 8T for human imaging. Participants will be told ahead

The Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) is doing this study because they want to learn more about eosinophilic gastrointestinal disorders (EGIDs).

This study aims to define new forms of diabetes that are not yet understood. Participants will be asked to provide medical and family history and may be asked to have clinical lab testing performed.

We are collecting data on children living with chronic kidney disease, including children on dialysis or with a kidney transplant, to learn more about what happens over time. The data collected will be used for research projects.

The goal of the study is to determine why some men and women get certain types of head and neck (mouth or throat) cancer, and others do not. If we can identify underlying causes of head and neck cancer, we can determine ways to prevent it from occurring. Collection and analysis of medical records and tumor biology may also lead to more effective treatments and lower the death rate from this disease.

The purpose of this research study is to compare how well two types of physical therapy (PT) programs work for people who have recently had total knee replacement (TKR). One program is typical postoperative PT. The other program is typical postoperative PT with additional balance training and physical activity coaching. By doing this study, we hope to provide people who have TKR in the future, as well as their health care providers, with information that will help people following TKR to increase their physical activity and improve their walking mechanics after TKR.

The purpose of this research study is to create a Lymphoma Registry of patients who are willing to complete the study's comprehensive assessment. The assessment is designed to gather information on memory, nutritional status, mental health, and level social support. It is also designed to understand how well you carry out your day to day activities and to briefly describe what other medical conditions you may have. This assessment will help your health care team determine your "functional age" (the age you function at) as compared to how many years old you are. We will also ask you to complete questionnaires that ask questions about your personal health history, such as exercise and smoking,

We have created this registry to provide an opportunity to study diagnostic capabilities, administration protocols and long-term effects of contrast-enhanced ultrasound (CEUS) of any organ.

Diabetic retinopathy (DR) is the leading cause of blindness in working age Americans. Vision loss due to DR can be prevented with early detection and treatment. However, the rate of retinopathy screening remains low. Pharmacies are often a patient's primary point of contact with the health profession. Hence, this study aims to determine the feasibility of integrating a portable handheld camera for eye screening without the need for pupil dilation at pharmacies located in rural and urban areas of North Carolina. The average consumer visits a pharmacy 35 times per year, making pharmacies an ideal setting for evaluating this DR screening model. Additionally, we will also assess the feasibility of integrating an automated grading system for retinal images. If successful, results from this study can be used to increase and improve community-based health care by integrating pharmacies and clinical care.

The purpose of this research study has two parts. One part is to determine if a new test of palatal closure during speech in 2 year-old children with repaired cleft palate will predict palatal closure at older ages. The other part is to find out if some common speech problems in children with repaired cleft palate get better as a child gets older.