The DNA that we can test from a nasal swab, can help us determine a patient's lung cancer risk. For patients with new lung nodules found on CT scans, we are offering this nasal swab test and collecting data on how physicians use test results to help assess risk and determine treatment strategies.
Hunter Syndrome or Mucopolysaccharidosis II (MPS II) is a rare genetic disorder caused by decreased levels of a specific enzyme, iduronate-2-sulfatase. Lack of this enzyme causes buildup of large sugar molecules called glycosaminoglycans (GAGs). The build up of GAGs causes significant damage to the body and brain. This study is evaluating the use of JR-141, an enzyme replacement therapy, to provide the missing enzyme to the body. This allows for break down of the stored GAGs. JR-141 uses specific technology to cross the blood brain barrier so that the enzyme can get into the brain. JR-141 is expected to help both the cognitive (brain) and body effects of MPS II.
To understand how participation in a long-duration professional development program influenced: (a) participants' knowledge, skills, self-efficacy for teaching STEM outdoors and (b) their STEM learning ecosystems.
Machine learning is a powerful tool for solving problems that involve a lot of data. It is being used in many different fields. The first step in creating a machine learning system is to understand what you want to achieve and then turn that goal into a plan for using machine learning. This is called problem formulation. Problem formulation is important because it not only helps you understand what you want to achieve but also helps you figure out if you have the right data to make it work. Practitioners need to try different approaches and see what works best for their data. This can take some trial and error. This study looks at a new tool designed to make problem formulation easier and see if it helps practitioners.
The purpose of this study is to measure improvements in liver fibrosis and inflammation with GSK4532990 compared with placebo in participants with NASH and advanced (F3) fibrosis.
We are seeking to improve knowledge around treatment of atrial fibrillation for primary care providers and patients through educational interventions.
To see if women who had breast cancer at ages 18-40 were able to successfully lactate and breastfeed after lumpectomy and radiation treatment afterwards.
This study aims to better understand how parenthood affects people with cystic fibrosis (CF). We will survey people with CF who are parents and those who are not and monitor health outcomes over time.
A case study of ten biomedical engineering programs in which two universities collaborate on at least a Ph.D. degree. The intent is to identify circumstances that lead to successful inter-university collaboration as measured by research output, including publications and patents, along with patent citations.
The goals of this research are to: (1) understand how hearing develops throughout the lifespan; (2) determine the factors associated with successful speech, language, and hearing outcomes for individuals spanning a wide range of ages and abilities; and (3) advance auditory assessment practices for both neurotypical and diverse populations.