To find out if the addition of 2 blocks of inotuzumab ozogamicin to the standard chemotherapy regimen will improve outcomes in children and young adults with High-Risk (HR) B-cell acute lymphoblastic leukemia (B-ALL).

To generate information on the undergraduate experience at the University of North Carolina at Chapel Hill from currently enrolled students. This survey is processed every other year.

The ASPIRE trial aims to study anticoagulant medications in patients who have had an intracerebral hemorrhage (bleeding in the brain) who also have atrial fibrillation (irregular heartbeats). Participants who agree to study participation will receive either Aspirin or Apixaban and followed for 12-36 months to see if they have any other strokes, and follow their general recovery after stroke.

We are exploring the relationship between participation in the FIT Program with health outcomes, recidivism, and healthcare utilization for people who are coming out of incarceration and who have chronic illnesses.

The purpose of this study is to determine which new magnetic resonance sequences provide better, faster and more useful information. A sequence is a distinct method of obtaining magnetic resonance (MR) images. A magnetic resonance imaging (MRI) exam is made up of many different imaging sequences. These new sequences will be implemented on either on a 3 Tesla (3T) MR system, a 7 Tesla (7T) MR system (single- or multi- transmit), or both. Since the signal-to-noise ratio for MR images is highly dependent on the magnetic field strength, the anticipated signal-to-noise will be 7T greater than 3T and 3T greater than 1.5T systems. The 3T MR system is FDA approved whereas the 7T system is not FDA approved, but is built to the same standards as other FDA approved scanners. In addition, the FDA has approved magnetic field strength up to 8T for human imaging. Participants will be told ahead

The primary purpose of this work is to engage a broad group of stakeholders to implement a patient-centered approach to the de-adoption of self-monitored blood glucose among non-insulin-treated patients with Type two Diabetes Mellitus. We will evaluate the effectiveness of Rethink the Strip finalize and package it for nationwide dissemination.

This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.

The purpose of this study is toevaluate the ergonomics of residents and surgical faculty during operations and identify correlations between body position, physician wellness and patient outcomes.

The purpose of this study is to delve into speakers' performance of vowel production, and the vowels tested here are perceived to be significantly unfamiliar based on the vowel inventory of the speakers' native language.

We are collecting data on children living with chronic kidney disease, including children on dialysis or with a kidney transplant, to learn more about what happens over time. The data collected will be used for research projects.