The purpose is to better understand the function of newly identified genes that when mutated cause the disease primary ciliary dyskinesia (PCD), or clinical disorders that share clinical features of PCD. PCD is a rare disease that is caused by defects in the structure or function of cilia that move mucus and inhaled foreign material, including bacteria and viruses, out of the airways. By understanding how the proteins encoded by these genes function and how this function is altered in disease, we may be able to improve the treatments available for PCD and other airway diseases.

The purpose of the study is to use a diagnostic evaluation and genetic testing to confirm a diagnosis of Primary Ciliary Dyskinesia (PCD) or Primary Immune Deficiencies (PID) in subjects who have presented with suppurative lung disease.

To evaluate the HomeLink program, which is a service designed to provide housing, case management and occupational therapy to individuals living with serious and persistent mental illnesses.

Develop a set of effective little cigar and cigarillo warning statements.

To study the how well Pembrolizumab works on advanced tumors

The purpose of this study is to implant abnormal human parathyroid glands into mice to be used to test agents that might allow better imaging of parathyroid glands. This may improve the surgery that is sometimes required for abnormal parathyroid glands.

The purpose of this study is to follow patients who were diagnosed with HIV-1 infection during this acute infection stage to look at clinical and laboratory markers of HIV infection, over time. Individuals joining this study may or may not be on treatment for their HIV. No treatment is provided in this study. Participants may be asked to provide blood samples on this study.

The purpose for this research study is to learn more about PCD through the creation of a secure electronic clinical registry. Through this registry, researchers will be able to follow people living with PCD over time to learn more about how PCD affects people's health and the treatment people take.

To evaluate the feasibility and acceptability of a novel psychosocial intervention for parents with advanced cancer and their co-parents.

The proposed study seeks to prospectively investigate the effects of oral steroid administration following injection laryngoplasty in patients suffering from glottic insufficiency in an attempt to shorten post-procedural recovery time.