The aim of this study is to collect detailed self-reported information on HIV-infected patients' clinical, socio-demographic and behavioral characteristics to better understand who is being affected by the HIV epidemic in North Carolina and the needs of this population.

The purpose of this study is to evaluate both sporadic (not inherited), and familial (inherited), forms of frontotemporal lobar degeneration (FTLD). Patients include both those who have symptoms of FTLD and those who do not (yet have a family history involving FTLD). This is an observational study, meaning that there is no investigational treatment involved. We will be working with patients for up to a 5 year period to learn more about FTLD using a neurological exam, tests of memory, behavior, and judgement, MRI, and biospecimen collection (blood and/or CSF). This study involves genetic testing of the genes so far identified to be associated with FTLD. The overall goal is to help better understand FTLD, to better understand the genetics of FTLD, and to use the information we learn to guide improved patient care and potential drug development.

Current dialysis vascular access patient education materials can be overwhelming, not written in plain language, and not have enough realistic information about the steps involved in getting a dialysis vascular access before starting hemodialysis. This study is being done to create and test a dialysis vascular access educational video for patients. Participants would take part in a one-time interview about their thoughts on dialysis vascular access education and their ideas for a vascular access video.

Speak with Medicaid providers about the upcoming change to how providers are reimbursed for services

The purpose of this research study is to understand how the management of Patient Reported Outcomes (PROs) could help improve surgical care for patients undergoing chest surgeries. PROs are symptoms directly reported by patients through the completion of a survey.

The purpose of this IRB approved Humanitarian Use of a device is to allow patients to be treated with LDL-Apheresis, using the LIPOSORBER® LA-15 system. This device is approved for adult and pediatric patients with Focal Segmental Glomeruloslerosis as a Humanitarian Use Device. Its effectiveness has not been demonstrated.

We aim to characterize work exposures and illness in Badin, North Carolina--the site of an aluminum smelting facility for nearly 100 years.

In an effort to improve therapeutic options for treatment, this study will explore the use of research laboratory testing results to guide treatment decisions for difficult to treat Mycobacterium abscessus and other non-tuberculous mycobacteria (NTM) infections. Specific combinations of antibiotics will be tested in the laboratory, alone or in combination, to determine if those antibiotics could help with treatment of individual patients.

To comprehensively characterize the clinical, laboratory, and histopathologic features of breast cancer patients receiving care according to local standards in Malawi.

The purpose of this study is to allow for the laboratory examination and characterization of inflammatory cells found in sputum, nasal cells and components in exhaled breath. Sputum samples may also be tested for the presence of proteins and genetic variations thought to be important in inflammation.