To evaluate the safety and efficacy of BLU-222 therapy in patients with advanced solid tumors.

Do you have stage 1, HER2-positive breast cancer? Has your surgery already been completed? If so, you may be able to take part in a study to help us learn more about a combination of medications to treat your cancer.

Have you been recently diagnosed with Acute Lymphoblastic Leukemia? If so, you may be able to take part in a research study to help us learn more about the effects of using Tyrosine Kinase Inhibitor (TKI), steroids and blinatumomab versus treatment with steroids, Tyrosine Kinase Inhibitor (TKI) and chemotherapy.

Do you plan to undergo radiation therapy for a cancer in the abdomen or pelvic region? You may be able to take part in a research study to help us learn if a fatty acid supplement can improve quality of life by limiting GI upset during radiation therapy.

Do you have small cell lung cancer, large cell neuroendocrine cancer, neuroendocrine prostate cancer, or gastroenteropancreatic neuroendocrine carcinomas? Have you been treated with existing standard of care treatments that did not work? You may be able to take part in a research study to test a new drug for these types of cancer.

Have you been diagnosed with Advanced Renal Cell Carcinoma? If so, you may be able to take part in a research study investigating the optimal way to combine or sequence therapies in patients with renal cell cancer with bone metastasis.

Have you been diagnosed with cancer or a benign disease that is being evaluated for cancer for which you may receive treatment? If so, you may be able to take part in a research study that collects biospecimens (e.g. blood, saliva, tissue, etc) and health information to better understand how cancers develop and affect the body,]. If so, you may be able to take part in a research study that aims to identify non-invasive biomarkers for cervical cancer screening and monitoring following treatment of abnormal areas on the cervix caused by HPV.

Have you been diagnosed with pleural fluid, and have been referred for a pleural fluid drainage? If so, you may be able to participate in a research registry to help us learn more about lung cancer.

The purpose of this study is to understand how monitoring symptoms at home after lung cancer diagnosis could impact quality of care and the likelihood of returning to the hospital. This study will also help us understand whether symptom monitoring in patients with advanced lung cancer is helpful for patients and the clinical teams who care for them.

Have you been diagnosed with Advanced Prostate Cancer? If so, you may be able to take part in an International Registry for Men.