The purpose of this study is to characterize the natural history of DRPLA patients using a variety of clinical and biomarker modalities and to identify genetic factors, biomarkers, and clinical measures that could predict disease progression.

The purpose of this study is to evaluate and compare the survival outcome of patients with first recurrence of GBM undergoing surgical debulking/resection followed by either implantation of the SC9 device and repeat BBB opening in association with carboplatin chemotherapy or standard of care second line chemotherapy with either lomustine or temozolomide (per best physician's choice and best practice).

The aim of this project is thus to explore people's judgments (e.g., fairness, efficiency) of different allocation procedures .

We are investigating whether appropriate lung screening guidelines are being followed.

To determine the effect of dual targeted therapy with an anti-integrin (vedolizumab [VDZ]) and a Janus kinase (JAK) inhibitor (tofacitinib [TOF]) on clinical remission.

The purpose of this study is to determine if a new medication is effective at treating cardiac amyloidosis.

The purpose of this study is to understand individuals experiences in supervisory and leadership roles in organizations. Leaders may engage in a variety of behaviors at work. The goal is to understand how these differing behaviors influence how leaders perceive their image that, then, influences their subsequent behaviors--of them engaging in effective leader interactions with employees and ineffective leader interactions with employees. The projects serves as the undergraduate honors thesis and will contribute to theory and research in the organizational sciences on leadership and employee-leader interactions.

This is a short survey that will help NC CEAL prioritize resources, programming, and support to alleviate the impact of COVID-19 in communities across North Carolina.

To test the pay-it-forward strategy as a means of increasing rates of testing for gonorrhea

This is a research study to evaluate the comparative effectiveness and tolerability of outpatient transrectal prostate biopsy versus transperineal prostate biopsy, both MRI-targeted.