This study is being done to answer the following question: Do two different anti-cancer drugs, paclitaxel (PTX) and pegylated liposomal doxorubicin (PLD) have similar effects on treating KS in PLWH in sub-Saharan Africa? We are doing this study because we want to find out if one of these approaches, PTX or PLD, is better than the other for KS. Both drugs may be given as part of the usual approach for your KS. The usual approach is defined as care most people get for KS.
This research examines how alternative food networks (AFNs) in Turkey enact autonomy by connecting various stakeholders, including small-scale producers, cooperatives, and consumers across the country, under a solidarity-based organization. Successful data collection will enable the researcher to obtain a deep understanding of the AFNs - specifically how they challenge the gendered production relations, maintain fair production and distribution chains, and finally, keep solidarity as the core principle of the network.
Women's Police Stations were established in Brazil in 1985 to respond to reports of violence against women. Since then, they have spread throughout Latin America, but they take different forms. I am interested in seeing what may make some Women's Police Stations more effective than others. It is important to know the conditions under which these stations do their jobs, to prevent and respond to violence against women.
More primary care healthcare providers are asking patients questions about their ability to access and pay for things they need, like transportation, food, and housing. The purpose of this research study is to better understand how healthcare providers, patients, and caregivers feel about asking and answering these types of questions.
The goal of this study is to examine the relationship between mental health concerns (e.g., anxiety, depression, and stress) and PAUSE-Cardio, a 6-week moderate-intensity cardiovascular exercise intervention program for women's sport student-athletes transitioning into college and collegiate sport. Under Purposeful, Authentic, and Unifying Student-Athlete Experiences (PAUSE) programming, this study is a cardiovascular comparison intervention with matched aims and methods to the ACC-CRIA funded PAUSE-Yoga study. This longitudinal study examines the feasibility and effectiveness of PAUSE-Cardio to mitigate anxiety, depression, and stress.
Domestic violence intervention programs (DVIPs), also known as batterer intervention programs (BIPs), are court-mandated and self-referred programs designed to address domestic violence perpetration through psycho-educational approaches and/or cognitive behavioral therapy. By building on the extant evidence base and conducting formative research, we will identify DVIPs that have demonstrated effectiveness and innovative practices, including the utilization of restorative justice frameworks, and assess their curricula, service delivery approaches, partnerships, and administrative structures. We will use this information as the basis to determine DVIP best practices, with the goal of improved outcomes in mitigating domestic violence.
We are surveying American adults to understand their attitudes toward salient political issues. Findings will help support efforts to decrease polarization and increase public support for key issues, such as climate change mitigation.
To assess if a facilitated curriculum using fine art improves clinical reasoning skills and tolerance of ambiguity in Internal Medicine interns.
The purpose of this research study is to understand how to better support learning while searching online. In this study, participants will be asked to: complete a search task online to learn about a particular topic, respond to questionnaires that ask about your experience before and after the search task, and complete an assessment immediately after the search task and one week later about the search task topic.
Hunter Syndrome or Mucopolysaccharidosis II (MPS II) is a rare genetic disorder caused by decreased levels of a specific enzyme, iduronate-2-sulfatase. Lack of this enzyme causes buildup of large sugar molecules called glycosaminoglycans (GAGs). The build up of GAGs causes significant damage to the body and brain. Idursulfase-IT, an enzyme replacement therapy, was developed for the treatment of patients with Hunter Syndrome with cognitive impairment to help with the central nervous system manifestations of the disease. The purpose of this post-trial access program is so that patients with Hunter syndrome who previously received monthly administration of idursulfase-IT through participation in an earlier clinical research study can continue to receive it.