This study will develop and test an online group course on self-compassion to help caregivers of children with physical disabilities manage stress and improve their well-being.

The purpose of this study is to identify factors that can aid in the design and implementation of a strong safety culture among Hispanic construction workers. The Carolina Center for Healthy Work Design and Worker Well-Being will partner with a global engineering and construction management services company to assess the safety culture and sense of inclusion for the Hispanic workforce, which ultimately contributes to a safer environment and an industry with less worker injuries and fatalities.

This project will evaluate two training models of an evidence-based online dementia care training for direct care staff in assisted living. It will examine the extent to which each training is able to be implemented by assisted living communities, and to the extent the trainings improve staff knowledge and attitudes, change care practices, and improve the wellbeing of staff, residents, and residents' family members. Results will inform next steps in dementia care training for the assisted living and broader long-term care workforce.

The purpose of our study will be to evaluate the effectiveness of a series of examination workshops (knee, shoulder, hip) delivered during an academic half-day for first year residents.

Mucopolysaccharidosis II (MPS II) or Hunter syndrome, is a rare genetic disorder caused by the decreased levels of a specific enzyme, iduoronate-2-sulfatase. Lack of this enzyme causes buildup of large sugar molecules called glycosaminoglycans (GAGs). The build up of GAGs causes significant damage to the body and brain. This study will evaluate the long-term use of DNL310, an enzyme replacement therapy, to provide the missing enzyme to the body and to break down the stored GAGs. DNL310 uses specific technology to cross the blood brain barrier so that the enzyme can get into the brain. DNL310 is expected to help both the cognitive (brain) and body effects of MPS II. This is an extension study to two current DNL310 clinical trials; only participants currently enrolled in these trials will have the opportunity to participate in this long-term study.

To assess the feasibility and acceptability of a statewide intervention to promote alternatives to incarcerations and evidence-based approaches to the treatment of pregnant and postpartum people experiencing incarceration and substance use disorder, we are conducting a virtual training for NC jail staff and will conduct pre- and post-training evaluations to assess knowledge gained about the topic.

A clinical study to investigate efficacy and safety of a new injectable drug to treat symptoms of thyroid eye disease

Study of drag artists and the music they use in performance.

The purpose of this study is to compare clinical outcomes and health-related quality of life between an individualized hemodialysis prescription and conventional hemodialysis prescription in individuals requiring chronic hemodialysis who still have residual kidney function.

It is well-documented in the literature that those who have performed well on standardized tests are likely to continue to perform well. This study will interview volunteers from UNC-CH School of Medicine that are high-performing test-takers, and otherwise, in an attempt to identify qualities, characteristics, or themes shared among those who consistently perform well on tests.