This study will look at the current health statuses of members of the Lumbee tribe. Health statuses of other tribes who have federal recognition will be put together in order to compare them to those of the Lumbee. This study hopes to see what exactly federal recognition could potentially do for the Lumbee tribe when it comes to health if they were to receive it.

The purpose of this study is to assess the effect of emotional support groups and educational webinars on the well-being of patients with rare dermatologic conditions characterized by blistering. Patients will be given a survey before and after participating in six support group and webinar meetings.

The purpose of the HEALEY ALS Platform Trial is to develop and administer various clinical trials under different regimens with ALS to provide multiple treatment options for patients with ALS.

To evaluate the safety of GBT021601 and its effect on sickle cell complications

Osteosarcoma is the most common primary bone malignancy of childhood and adolescence. Survival rates for patients with standard risk (localized, resectable primary tumors) and high-risk disease (presence of metastases, unresectable or primary pelvic tumors) are 70% and 20-30%, respectively, and have remained unchanged for several decades despite numerous attempts to augment standard therapies. Multi-targeted receptor tyrosine kinase inhibitors (MTKIs), such as cabozantinib, can target signaling pathways that are known to be altered in osteosarcoma. Several MTKIs including cabozantinib have recently shown clinical evidence of activity in prospective studies for both pediatric and adult patients with advanced osteosarcoma. Furthermore, feasibility of administering MTKIs in combination with cytotoxic chemotherapy has previously been shown in patients with AML, hepatocellular carcinoma, and soft tissue sarcomas. Osteosarcoma is the most common primary bone malignancy of childhood and adolescence. Survival rates for patients with standard risk (localized, resectable primary tumors) and high-risk disease (presence of metastases, unresectable or primary pelvic tumors) are 70% and 20-30%, respectively, and have remained unchanged for several decades

To demonstrate efficacy of Bexsero in prevention of urogenital and/or anorectal gonococcal infection. To estimate efficacy of Bexsero in prevention of overall gonococcal infection and by anatomical site (urogenital, anorectal or pharyngeal). To assess safety of Bexsero.

All existing studies estimate the health effects of disability insurance based on reduced form models. This paper fills the gap in the literature by developing a model that allows the estimation of the Social Security Disability Insurance effects on health in a structural way. The structural model enables me to analyze counterfactual scenarios. In particular, I concentrate on the modification of the SSDI program that permits partial benefits for the partially disabled.

The purpose of this study is to understand the relationship between binge drinking in adolescence and behavior in adulthood, as well as the relationship between sleep and reactions to alcohol.

Researchers from the University of North Carolina at Chapel Hill are seeking input from community members interested in joining a Community Advisory Board (CAB) with a focus on improving knowledge around the impacts of extreme weather-related disasters and healthcare access. The purpose of this CAB is to ensure the proposed research remains relevant and useful to the broader community in all phases of research - from forming partnerships to using research results to inform policy and advocacy actions.

The purpose of this study is to learn more about the experiences of families with children who have peanut or other food allergies. It also explores parents' (or other caregivers') and adolescents' perceptions of available food allergy treatments, as well as clinical research options.