This study wants to learn how people with cancer manage their day-to-day health and treatment while receiving medicines for cancer. We will ask patients about their experiences through short surveys and interviews to understand what helps them stay well and avoid emergency visits or hospital stays. The goal is to find ways to better support patients during treatment, especially those who live farther from the hospital or have fewer resources.

The purpose of this study is to assess how the use of community health-workers for human papillomavirus (HPV) testing influences the number of women living with HIV who get screened for cervical cancer.

Pleuropulmonary Blastoma (PPB) is a rare lung tumor in young children that can grow in stages from less serious (Type I) to more dangerous (Type III). This study will test how well a drug combo: vincristine, topotecan, and cyclophosphamide (VTC) works for serious types (Type II and III) and help decide which patients with less serious tumors (Type I and Type Ir (regressed) PPB ) need chemotherapy after surgery. Researchers will also study the biology of the tumor to learn more about it.

To compare the prevalence, severity, and timing of chronic health conditions (CHC) in a cohort of patients with DS-AL (Down Syndrome Acute Leukemia) with age-comparable DS individuals that have no cancer history. Our secondary objectives will compare NP (Neuro-Psychological) and health-related quality of life outcomes in survivors of DS-AL compared with age-comparable DS individuals with no cancer history, and will identify risk determinants of CHC and NP late effects among survivors of DS-AL.

Ovarian cancer is the second most frequently diagnosed gynecologic cancer in the United States. Although it is the eleventh most common cancer among women, ovarian cancer is the fifth leading cause of cancer-related death. Fortunately, survival rates for ovarian cancer patients have been improving over the past few decades due to advances in medical procedures and the availability of new cancer drugs. However, studies have shown that the improvement of clinical outcomes are unequal among patients of different racial and ethnic backgrounds. This study seeks to understand the factors associated with healthcare disparities in Black ovarian cancer patients and identify features of programs that have been successful in addressing these racial imbalances. The findings of this study will help the researcher develop future programs to address healthcare disparities in Black ovarian cancer patients.

We are collecting blood and optionally stool, bone marrow or tissue samples from patients who received cell therapy or a stem cell transplant to treat cancer. This will help understand how the immune system recovers after cell therapy or stem cell transplant and how it may relate to patient outcomes.

The purpose of this study is to improve the treatment of children and young adults with all stages of FHWT, so that more patients are cured without relapse, and that side effects from treatment are lessened without decreasing cure rates. This study will use information on higher or lower risk features of FHWT to adjust the treatment of each subject based on their risk of relapse.

This study will collect information from colorectal surgeons throughout the United States with regard to their access to pelvic exenteration surgery for their patients with rectal cancer. We will assess their personal comfort with performing the procedure as well as their perceived access to colleagues who can provide the procedure. We will also assess educational and support needs amongst colorectal surgeons with regard to pelvic exenteration.

This study is looking at how platelets-blood cells that help stop bleeding-are collected, processed, and used for cancer patients in Malawi. Right now, platelet supplies are limited, and some transfusions are delayed or not completed. We want to understand what happens at each step, from the blood donors who give blood, to the Malawi Blood Transfusion Service where platelets are prepared, to the hospitals where patients receive them. By reviewing donor and lab records, tracking transfusions, and talking with doctors, nurses, and lab staff, we hope to find simple, realistic ways to improve the process. The goal is to make platelet transfusions safer, faster, and more reliable for patients who need them most.

To gather information on the technique of staging laparoscopy and processing of peritoneal washings through a survey of practicing surgical oncologists. This presents an opportunity to potentially standardize this procedure in future. This may help facilitate more accurate staging of the peritoneum.