This study will investigate how mechanical properties of breast tissue, such as stiffness, viscosity, and anisotropy, are related to breast tumor malignancy and response to chemotherapy. The study uses ultrasound imaging to measure these mechanical properties non-invasively in human subjects.

The goal of this study is to look into the patient-reported and functional outcomes of patients who have undergone total femoral replacement or osseointegrated amputation for oncologic and traumatic indications. We want to see if functional and patient-reported outcomes are correlated and if patient satisfaction with the implants differs between surgical indications.

To provide AMTAGVI per United States Prescribing Information (USPI) to patients.

The purpose of this study is to determine if treating germinomas with chemotherapy followed by a lower dose of radiotherapy (RT) can be as effective as the current standard of care. Specifically, our primary aim is to determine whether 12 Gy whole ventricular irradiation (WVI) and 12 Gy tumor boost would maintain similar efficacy compared to ACNS1123 stratum 2 as measured by event-free survival (EFS) in eligible patients with localized primary central nervous system (CNS) germinoma who present with serum and/or CSF human chorionic gonadotropin-beta (hCGß) = 100 IU/L and normal AFP, and meet complete response (CR) or continued complete response (CCR) criteria following chemotherapy/second-look surgery (Stratum 1). We are attempting to build upon the excellent results of ACNS1123 stratum 2 by reducing the RT dose even further for patients in a CR after chemotherapy.

The purpose of this single-arm phase 2 study is to evaluate the efficacy of digoxin in treating relapsed non-SHH, non-WNT medulloblastoma in pediatric and young adult patients.

To understand the relationship between biomarkers (found in the blood) and health outcomes among adults diagnosed with hepatocellular carcinoma who are receiving a liver transplant.

The goal of this study is to assess the feasibility of a nutrition program for individuals with cancer who are undergoing treatment. The nutrition program includes counseling from a registered dietitian, food logging, and nutrition symptom tracking.

To compare the prevalence, severity, and timing of chronic health conditions (CHC) in a cohort of patients with DS-AL (Down Syndrome Acute Leukemia) with age-comparable DS individuals that have no cancer history. Our secondary objectives will compare NP (Neuro-Psychological) and health-related quality of life outcomes in survivors of DS-AL compared with age-comparable DS individuals with no cancer history, and will identify risk determinants of CHC and NP late effects among survivors of DS-AL.

The study purpose is to find out if (a) it's possible to deliver healthy frozen meals to homes of children receiving chemotherapy, and (b) the meals are acceptable to the children and their families.

To collect quantitative data to: -Primarily gain a better understanding of patients' attitudes and preferences regarding end-of-life care management if they were to develop a high-risk skin cancer. To be more specific, we hope to gain a better understanding of how patients weigh their risk of developing skin cancer while taking immunosuppressants versus the risk of transplant rejection should they choose to stop or lower their immunosuppressants. -Determine how far these kidney transplant recipients travel to obtain skin-related care -Determine how frequently kidney transplant recipients obtain skin exams -Determine patients' baseline knowledge regarding risk of skin cancer while taking immunosuppressants, which are medicines that lowers immune systems -Determine the quality of life of individuals with skin cancer who are kidney transplant recipients