Purpose: to establish a Registry of pediatric patients treated with proton radiation therapy. Participants: Patients who are less than or equal to 21 years old at time of treatment start and treated with radiation therapy at one of the participating centers. Procedures (methods): This Proton and Photon Consortium Registry (PPCR) enrolls children treated with radiation therapy to form an expansive description of the pediatric population that receives protons and to better catalogue the benefits of protons, in this cohort. The data will also be used to evaluate practice differences and help facilitate collaborative research across the various radiation centers. The PPCR collects an expanded set of demographic and clinical data that will enhance the practice data that many participating radiation centers already collect in their routine operations. The PPCR has been expanded to include a photon-treated control group, helping to facilitate comparative effectiveness analysis.
The expected outcome of this proposal is a novel care pathway delivered by pharmacists to improve side effects during oral chemotherapy for patients, a known barrier to adherence, and ultimately to prevent progression and early mortality. Our long-term goal for P3OC is to develop and test new dashboard features to optimize pharmacy care and meet future needs for value-based payment models
This study will evaluate the use of MMUD PBSC in adults and explore the safety and efficacy of MMUD BM in pediatric recipients with hematological malignancies who may lack other donor options.
To create digital tools to support young adult cancer survivors completing active treatment and transitioning into survivorship care.
The purpose of the study is to determine how the Cancer Prevention and Control Research Network (CPCRN) researchers and their community partners are operationalizing the nine health equity Principles adopted by the network. The examples, acquired through in-depth interviews, will be used to develop a technical assistance toolkit for CPCRN and the general research community.
This study seeks to understand how best to increase knowledge about clinical trials, best way of communicating information about clinical trials, and suggestions for improving clinical trial participation particularly among African Americans (AA).
The purpose of this research study is to create a Lymphoma Registry of patients who are willing to complete the study's comprehensive assessment. The assessment is designed to gather information on memory, nutritional status, mental health, and level social support. It is also designed to understand how well you carry out your day to day activities and to briefly describe what other medical conditions you may have. This assessment will help your health care team determine your "functional age" (the age you function at) as compared to how many years old you are. We will also ask you to complete questionnaires that ask questions about your personal health history, such as exercise and smoking,
The goal of the study is to determine why some men and women get certain types of head and neck (mouth or throat) cancer, and others do not. If we can identify underlying causes of head and neck cancer, we can determine ways to prevent it from occurring. Collection and analysis of medical records and tumor biology may also lead to more effective treatments and lower the death rate from this disease.
To find out if the addition of 2 blocks of inotuzumab ozogamicin to the standard chemotherapy regimen will improve outcomes in children and young adults with High-Risk (HR) B-cell acute lymphoblastic leukemia (B-ALL).
The purpose of this research study is to learn more about Barrett's Esophagus and esophageal cancer by collecting data and samples (blood and tissue) for a biorepository. A biorepository is a large bank of specimens and data that are stored indefinitely and may be shared with other researchers.