Better understand symptoms that occur after liver-directed treatments for liver cancer

The purpose of this study is to develop a prospective longitudinal cohort/registry of lymphoma patients in Malawi to address a lack of prospective longitudinal data related to lymphoma in sub-Saharan Africa, and to serve as a foundation for developing optimal treatment strategies in this challenging environment.

This study is being conduced to assess the feasibility of conducting multi-center prospective studies on surgical excision of suspected OSSN lesions in SSA in people living with HIV/AIDS (PLWHA).

The CMR is a population based breast imaging registry for women screened for breast cancer in NC.

The purpose of this research study is to assess the patient-level, healthcare provider/system-level, and community-level barriers to resolving abnormal mammograms and initiation of treatment of breast cancer in the 3 geographic regions of North Carolina: the greater Charlotte area, the Northwest, and the Northeast. These areas include the following counties: Anson, Cabarrus, Cleveland, Gaston, Lincoln, Mecklenburg, Stanly, Union, Edgecombe, Halifax, Nash, Northampton, Wilson , Ashe, Alleghany, Surry, Stokes, Watauga, Wilkes, Yadkin, Forsyth, Avery, Caldwell, Alexander, Iredell, Davie, Davidson, Burke, Catawba, and Rowan. These barriers can include obtainment of biopsies and other diagnostic procedures for resolving abnormal mammograms abnormalities or breast symptoms, access to care providers after breast cancer diagnosis, and initiation of appropriate surgical, chemotherapy, and radiation treatments after diagnosis.

We will identify changes in the numbers, seriousness, and outcomes of breast cancers diagnosed during the COVID-19 pandemic, compared to before the pandemic.

For more information, please visit our website: https://cecs.unc.edu The purpose of this research study is to learn more about the diagnosis, treatment, and survivorship experiences of adults with endometrial cancer. Initial enrollment goals are for 1,800 adults living in North Carolina at the time of their recent first diagnosis of endometrial cancer. This project will provide important data for integrating tumor biology, access to care, and other factors to identify contributors, and potential areas for intervention to address endometrial cancer disparities. Study staff will pursue annual follow-ups with participants, requesting updates to treatment status and quality of life measures for approximately 5yrs.

The purpose of this study is to create a biobank by collecting and storing specimens, such as blood and tissue, along with medical information such as demographics and treatment, from a large group of patients with pancreatic tumors. This biobank can then be used by future studies focused on pancreatic tumors.

In Aim 1, we will use existing research and expert review to develop new text and pictorial LCC warnings and test the new warnings using online experiments to identify warnings that adult LCC users perceive as most effective. The proposed study will fill critical gaps regarding which characteristics make LCC warning labels most effective and provide needed evidence on how LCC warnings influence LCC behavioral intentions. Our overarching goal is to develop effective LCC warnings that reduce cancer and other health risks.

The purpose of this study is to understand how your gut plays a role in how well CAR T cell therapy works. Your gut is home to bacteria, which we call the gut microbiome. The gut microbiome can send signals to your immune cells, which may impact how well and how long CAR T cell therapy will last. We can find out what type of bacteria are in your gut microbiome by studying your stool. We can understand more about the signals sent to the immune system by studying your blood. We will ask for stool and blood at the same time points throughout your treatment. We will study the identities and function of the bacteria and immune cells to understand more about how these signals work during CAR T cell treatment.