To comprehensively characterize the clinical, laboratory, and histopathologic features of breast cancer patients receiving care according to local standards in Malawi.

We aim to characterize work exposures and illness in Badin, North Carolina--the site of an aluminum smelting facility for nearly 100 years.

To evaluate the feasibility and acceptability of a novel psychosocial intervention for parents with advanced cancer and their co-parents.

To study the how well Pembrolizumab works on advanced tumors

The purpose of this study is to find better ways to diagnose, treat and prevent cancers in children, adolescents and young adults. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

The purpose of the DETECT study is to learn more about how some breast tissue features show up on a mammogram and what these features can tell us about the potential for a breast cancer diagnosis. Your participation will help us understand how the appearance of those breast tissue features is affected by hormone levels. Our objective is to collect urine samples that we will use to measure hormone levels. We will examine how hormone levels are related to breast tissue features measured from a breast cancer screening mammogram.

To assess the safety of nonconforming lisocabtagene maraleucel in patients

The purpose of this study is to understand how your gut plays a role in how well CAR T cell therapy works. Your gut is home to bacteria, which we call the gut microbiome. The gut microbiome can send signals to your immune cells, which may impact how well and how long CAR T cell therapy will last. We can find out what type of bacteria are in your gut microbiome by studying your stool. We can understand more about the signals sent to the immune system by studying your blood. We will ask for stool and blood at the same time points throughout your treatment. We will study the identities and function of the bacteria and immune cells to understand more about how these signals work during CAR T cell treatment.

The main purpose of this study is to determine how much MRTX849 can safely be administered to people. This will include looking at what side effects occur and how often they occur.

This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and other indications. This protocol will allow access to cord blood units that are unlicensed.